A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac …

KS Kim, ES Yang, DS Kim, DW Kim, HH Yoo… - Drug …, 2017 - Taylor & Francis
… a powerful oral drug delivery system for an oily drug, PLAG. … is still unsatisfactory, because
an oily drug hardly dissolves in the … of an oily drug to a practical solid pharmaceutical product. …

[HTML][HTML] Comparison of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded self-emulsifying granule and solid self-nanoemulsifying drug delivery system: powder …

DS Kim, JS Kim, SJ Lim, JO Kim, CS Yong, HG Choi… - Pharmaceutics, 2019 - mdpi.com
… Owing to its oily properties, PLAG is practically insoluble in water, resulting in low … drug,
and liquid SMEDDS have poor flow ability [23]. The flow ability and bioavailability of oily drugs

Effect of inorganic mesoporous carriers on 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded solid self-emulsifying drug delivery system: Physicochemical …

DS Kim, ES Yang, CS Yong, YS Youn, KT Oh… - Colloids and Surfaces B …, 2017 - Elsevier
The purpose of this study was to assess the impact of inorganic mesoporous carriers on the
physicochemical properties and oral bioavailability of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-…

Degradation kinetics study of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) by a validated stability-indicating RP-HPLC method

KS Kim, ES Yang, DS Kim, DW Kim, CS Yong… - … of Pharmaceutical and …, 2018 - Elsevier
… Moreover, PLAG is an oily drug which is poorly water-soluble. However, it is freely soluble
in acetonitrile and alcohol [16], [17]. Different mobile phase proportions of acetonitrile: …

Synthesis of glycero amino acid-based surfactants. Part 1. Enzymatic preparation of rac-1-O-(N α-acetyl-l-aminoacyl) glycerol derivatives

C Morán, MR Infante, P Clapés - Journal of the Chemical Society …, 2001 - pubs.rsc.org
… All these features make them very attractive as dispersants, drug carriers and bactericides
… Then, the oily residue was dissolved with plain, deionized water and purified as described …

Iodoaryl analogs of dioctanoylglycerol and 1-oleoyl-2-acetylglycerol as probes for protein kinase C

LM Strawn, RE Martell, RU Simpson… - Journal of medicinal …, 1989 - ACS Publications
… 26, Reduction of 26 with sodium borohydride followed by acetylation and detritylation afforded
the diacylglycerol 3. Although the acetyl group was particularly prone to migration to the 3-…

[引用][C] A solid self-nanoemulsifying drug delivery system containing an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol for improved stability and oral …

최한곤 - 2018 International Conference of The Korean Society …, 2018 - scholarworks.bwise.kr
ScholarWorks@Hanyang University ERICA Campus: A solid self-nanoemulsifying drug
delivery system containing an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol for …

Development of PLAG-loaded solid SNEDDS formulation

ES Yang - 2017 - repository.hanyang.ac.kr
drug delivery system (SNEDDS) of water insoluble oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac–…
would be recommended as a powerful oral drug delivery system for an oily drug, PLAG. …

Facile synthesis of platelet-activating factor and racemic analogs containing unsaturation in the sn-1-alkyl chain

JR Surles, RL Wykle, JT O'Flaherty… - Journal of medicinal …, 1985 - ACS Publications
… peak time of drug activity. Fifty animals, divided among four … The lyso lipid was acetylated
to give a mixture of PAFs whose … give a yellow, oily residue that was dried under high vacuum …

[引用][C] … solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac …

최한곤 - 2018 Spring International Convention of The …, 2018 - scholarworks.bwise.kr
ScholarWorks@Hanyang University ERICA Campus: A novel solid self-nanoemulsifying
drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily …