Formulation and In-vivo Evaluation of Azatanavir Selfnanoemulsifying Drug Delivery System
KD REDDY, P Sandhya, P Mamatha - … Sciences and Drug …, 2022 - ijpsdronline.com
… A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability
and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-racglycerol. Drug deliv…
and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-racglycerol. Drug deliv…
Asymmetric synthesis of all stereoisomers of α-methylthreonine using an organocatalytic Steglich rearrangement reaction as a key step
FR Dietz, H Gröger - Synthesis, 2009 - thieme-connect.com
… drugs, and numerous methods for their synthesis exist. [³] … β-keto-α-amino acid ester rac-8
using sodium borohydride and … -acetyl-4-methyl-2-phenyloxazol-5-one (7; 52 mg) as an oily …
using sodium borohydride and … -acetyl-4-methyl-2-phenyloxazol-5-one (7; 52 mg) as an oily …
[HTML][HTML] Microfluidics for nano-drug delivery systems: from fundamentals to industrialization
H Zhang, J Yang, R Sun, S Han, Z Yang… - Acta Pharmaceutica Sinica …, 2023 - Elsevier
… nm, consisting of drugs and functional drug nanocarriers prepared … drugs to the desired site
and realize the drugs' sustained release, thereby reducing drugs' toxicity and improving drugs…
and realize the drugs' sustained release, thereby reducing drugs' toxicity and improving drugs…
Development of a Novel Chemoenzymatic Process for 3-(Methylsulfonyl)-l-phenylalanine Phenylmethyl Ester─A Key Intermediate of Lifitegrast (Xiidra)
C Wu, H Guo, J Tang, L Xia, J Shao, Y He… - … Process Research & …, 2024 - ACS Publications
… for the removal of N-acetyl group, 7 different lipases, acylases… converted back to a racemic
mixture (rac)-6 via oxazolone (… The yellow oily liquid 10 was dissolved in EtOAc (1.0 L). Then…
mixture (rac)-6 via oxazolone (… The yellow oily liquid 10 was dissolved in EtOAc (1.0 L). Then…
[HTML][HTML] The Impact of Polymers on Enzalutamide Solid Self-Nanoemulsifying Drug Delivery System and Improved Bioavailability
SM Lee, JG Lee, TH Yun, CH Kim, JH Cho, KS Kim - Pharmaceutics, 2024 - mdpi.com
Enzalutamide (ENZ), marketed under the brand name Xtandi ® as a soft capsule, is an
androgen receptor signaling inhibitor drug actively used in clinical settings for treating prostate …
androgen receptor signaling inhibitor drug actively used in clinical settings for treating prostate …
Syntheses of racemic and non-racemic silicon-and germanium-containing α-amino acids of the formula type H2NCH (CH2ElR3) COOH (El= Si, Ge; R= organyl) and …
M Merget, K Günther, M Bernd, E Günther… - Journal of Organometallic …, 2001 - Elsevier
… of the α-amino acids rac-2–rac-6 and on the chromatographic resolutions of rac-2 and …
The solvent was removed under reduced pressure and the oily residue distilled in a Kugelrohr …
The solvent was removed under reduced pressure and the oily residue distilled in a Kugelrohr …
Small-molecule inhibitors as potential therapeutics and as tools to understand the role of phospholipases A2
A Nikolaou, MG Kokotou, S Vasilakaki… - Biochimica et Biophysica …, 2019 - Elsevier
… classes of drug targets [1]. Small-molecule enzyme inhibitors have transformed human
medicine and it is estimated to comprise roughly one-third to half of all marketed drugs [2]. Since …
medicine and it is estimated to comprise roughly one-third to half of all marketed drugs [2]. Since …
Organosilicon molecules with medicinal applications
AK Franz, SO Wilson - Journal of Medicinal Chemistry, 2013 - ACS Publications
… fluorinated drugs (5-fluorouracil and flucytosine) was investigated, and results demonstrated
that the release of these fluorinated drugs occurs more slowly than a nonfluorinated drug (…
that the release of these fluorinated drugs occurs more slowly than a nonfluorinated drug (…
Design, Synthesis and Evaluation of 1, 3-Diaryl Pyrazoles as Inhibitors of GGTase-I, a Target for Anti-Cancer Drugs
M Mansha - 2017 - search.proquest.com
… Proteins modified by GGTase-I include GTPases in the Rho and Rac families, and many G
protein γ subunits. The two CaaX prenyltransferases require the Cys residue fourth from the C-…
protein γ subunits. The two CaaX prenyltransferases require the Cys residue fourth from the C-…
Lipase-mediated 'meso-tricks' to transform latently symmetrical d-aldoses into l-aldoses via alditols
GD Gamalevich, BN Morozov, AL Vlasyuk… - Tetrahedron, 1999 - Elsevier
… of antieancer, antiviral and antidiabetes drugs, or else as an … 1-O-acetyl2,3:4,5-di-O-isopropylidene-DL-xylitol
(rac-16a) … combined, and concentrated to leave an oily residue that was …
(rac-16a) … combined, and concentrated to leave an oily residue that was …