Effect of age and sex on the level of DNA strand breaks and oxidatively damaged DNA in human blood cells

P Møller - Mutation Research/Genetic Toxicology and …, 2019 - Elsevier
… age and sex on basal levels of oxidatively damaged DNA in leukocytes. In summary, the
results indicate influences of both age and sex on DNA damage in the comet assay, which may …

Variation in assessment of oxidatively damaged DNA in mononuclear blood cells by the comet assay with visual scoring

L Forchhammer, EV Bräuner, JK Folkmann… - …, 2008 - academic.oup.com
… of DNA damage in different units. We investigated the variation of DNA damage in mononuclear
blood cells (… unwinding and electrophoresis time, number of cells scored, as well as the …

Dietary antioxidants and beneficial effect on oxidatively damaged DNA

P Møller, S Loft - Free Radical Biology and Medicine, 2006 - Elsevier
… levels of oxidatively damaged DNA in white blood cells and … urinary excretion of oxidatively
damage DNA. In conclusion, this … of DNA damage in white blood cells and urine of humans, …

[HTML][HTML] Age and metabolic risk factors associated with oxidatively damaged DNA in human peripheral blood mononuclear cells

M Løhr, A Jensen, L Eriksen, M Grønbæk, S Loft… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… Aging is associated with oxidative stress-generated damage to DNA and this could be …
between levels of oxidatively damaged DNA in peripheral blood mononuclear cells (PBMCs) and …

Association between age and repair of oxidatively damaged DNA in human peripheral blood mononuclear cells

M Løhr, A Jensen, L Eriksen, M Grønbæk, S Loft… - …, 2015 - academic.oup.com
… and repair activity of oxidatively damaged DNA in PBMCs from humans. The association was
… repair activity of oxidatively damaged DNA in human blood cells have been investigated in …

Acute hypoxia and reoxygenation-induced DNA oxidation in human mononuclear blood cells

L Risom, C Lundby, JJ Thomsen, L Mikkelsen… - Mutation Research …, 2007 - Elsevier
… The levels of strand breaks and oxidatively damaged purine bases, measured by the comet
… in DNA repair of oxidatively damaged DNA were investigated in mononuclear blood cells (…

Copper (II) generates ROS and RNS, impairs antioxidant system and damages membrane and DNA in human blood cells

N Husain, R Mahmood - Environmental Science and Pollution Research, 2019 - Springer
… Several studies support that oxidative damage induced by ROS plays a key role in Cu
toxicity. For example, Cu is capable of inducing DNA strand breaks and oxidation of bases via …

[HTML][HTML] Comparison of oxidative stress/DNA damage in semen and blood of fertile and infertile men

J Guz, D Gackowski, M Foksinski, R Rozalski… - PLoS …, 2013 - journals.plos.org
… describe oxidative stress and oxidatively damaged DNA and repair were analyzed in the
groups of fertile and infertile subjects. These parameters include: (i) 8-oxodG level in DNA

Oxidative damage to DNA in diabetes mellitus

P Dandona, K Thusu, S Cook, B Snyder, J Makowski… - The Lancet, 1996 - thelancet.com
… To test whether DNA is also oxidatively damaged in … for oxidative damage to DNA, our
observations show that diabetic patients have significantly increased oxidatively damaged DNA. …

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

FM Yakes, B Van Houten - Proceedings of the National …, 1997 - National Acad Sciences
… This technique is based on the premise that DNA lesions, including oxidative damage
such as strand breaks, base modifications, and AP sites, will block the progression of the …