Molecular mechanism of phenotypic modulation of smooth muscle cells

K Sobue, K Hayashi, W Nishida - Hormone research, 1998 - karger.com
Phenotypic modulation of smooth muscle cells is closely associated with vasculogenesis, …
During phenotypic modulation, smooth muscle cells change their morphology, cell function …

Smooth muscle phenotypic modulation—a personal experience

JH Campbell, GR Campbell - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
… induce a change in the phenotype of smooth muscle cells in vitro and then stimulate their …
to induce a change in the phenotypic expression of smooth muscle cells. Our results further …

Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation

BN Davis-Dusenbery, C Wu, A Hata - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
The phenotype of vascular smooth muscle cells (VSMCs) is … In a cellular process known as
phenotype switching, VSMCs alternate between a contractile and synthetic phenotype state. …

Invited review: molecular mechanisms of phenotypic plasticity in smooth muscle cells

AJ Halayko, J Solway - Journal of applied physiology, 2001 - journals.physiology.org
… accumulation of a myofibroblast-like synthetic phenotype. These synthetic SMCs may be
derived from medial myocytes that undergo phenotypic modulation from a contractile state (15, …

Expression of high and low molecular weight caldesmons during phenotypic modulation of smooth muscle cells.

N Ueki, K Sobue, K Kanda, T Hada… - Proceedings of the …, 1987 - National Acad Sciences
… in nonmuscle tissues and cells. Therefore, the … smooth muscles. We then examined the
expressional changes of two caldesmons during phenotypic modulation of smooth muscle cells (…

Vascular smooth muscle cell phenotypic modulation in culture is associated with reorganisation of contractile and cytoskeletal proteins

NF Worth, BE Rolfe, J Song… - Cell motility and the …, 2001 - Wiley Online Library
… the process of SMC phenotypic modulation is associated not … However, with modulation to
the synthetic phenotype and loss … in cell function associated with SMC phenotypic change is …

Smooth muscle phenotypic modulation: role in atherogenesis

GR Campbell, JH Chamley-Campbell - Medical Hypotheses, 1981 - Elsevier
… the smooth muscle cells must be stimulated to phenotypically modulate to … cells after they
have modulated. In the body of the media a substance is produced by the smooth muscle cells

Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids

K Hayashi, M Takahashi, W Nishida, K Yoshida… - Circulation …, 2001 - Am Heart Assoc
phenotypic modulation, suggesting that these molecules could function as atherogenic factors.
The phenotypic modulation of vascular smooth muscle cells (… results in cell proliferation …

The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype: direct demonstration of phenotypic modulation

ME Sandison, J Dempster… - The Journal of …, 2016 - Wiley Online Library
… into a ‘synthetic’ migratory phenotype, so-called phenotypic modulation, whilst plaque …
cells. Recently, these views have been challenged, with reports that SMC phenotypic modulation

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin

ZP Liu, Z Wang, H Yanagisawa, EN Olson - Developmental cell, 2005 - cell.com
cellular responses. However, the potential role of Foxo proteins in phenotypic modulation
of … Here we investigate the effect of Foxo4 on phenotypic modulation of vascular SMCs. We …