Tocilizumab in isolated polymyalgia rheumatica: a systematic literature review

M Akiyama, Y Kaneko, T Takeuchi - Seminars in Arthritis and Rheumatism, 2020 - Elsevier
… showed that tocilizumab treatment led to a 58% reduction in the cumulative glucocorticoid
dose in the tocilizumab group compared with the glucocorticoid monotherapy group (Table 3). …

Alternatives to glucocorticoid monotherapy in the treatment of polymyalgia rheumatica

K Walz, L Elliott, T Pearson - … of the American Association of Nurse …, 2022 - journals.lww.com
polymyalgia rheumatica (PMR) can be challenging. The most efficacious and cost-effective
treatment of PMR is some type of glucocorticoid … alternatives to glucocorticoid monotherapy in …

Drug therapies for polymyalgia rheumatica: a pharmacotherapeutic update

MA González-Gay, T Pina, D Prieto-Peña… - Expert Opinion on …, 2018 - Taylor & Francis
glucocorticoid-sparing effect [Citation59]. In contrast, none of the PMR patients used as
controls, who were treated with glucocorticoids in monotherapy, reached glucocorticoid-free …

Effect of tocilizumab on disease activity in patients with active polymyalgia rheumatica receiving glucocorticoid therapy: a randomized clinical trial

V Devauchelle-Pensec, G Carvajal-Alegria, E Dernis… - Jama, 2022 - jamanetwork.com
… for patients with glucocorticoid-dependent polymyalgia rheumatica. IL-… active
glucocorticoid-dependent polymyalgia rheumatica. … with glucocorticoid-dependent polymyalgia

AB0529 Long-Term Glucocorticoid Monotherapy Can Lead To Remission in Japanese Patients with Polymyalgia Rheumatica without Notable Adverse Effects

A Aoki, A Senuma, A Osada, S Nagaoka - 2016 - ard.bmj.com
Polymyalgia rheumatica (PMR) is a common inflammatory condition of elderly persons. Clinical
symptoms are improved by low-dose glucocorticoids (… of GC monotherapy until remission …

Treatment of polymyalgia rheumatica

S Castañeda, N García-Castañeda… - Biochemical …, 2019 - Elsevier
glucocorticoids or with relapsing disease require other therapies aimed mainly to spare
glucocorticoids. … Another randomized control trial with etanercept in monotherapy versus placebo …

Efficacy of rituximab in patients with polymyalgia rheumatica: a double-blind, randomised, placebo-controlled, proof-of-concept trial

DE Marsman, N den Broeder… - The Lancet …, 2021 - thelancet.com
… we did not expect rituximab to show relevant efficacy before 11 weeks after infusion in most
patients with polymyalgia rheumatica. Therefore, we started with a regular glucocorticoid

Tocilizumab monotherapy for polymyalgia rheumatica: a prospective, single‐center, open‐label study

K Chino, T Kondo, R Sakai, S Saito… - International Journal …, 2019 - Wiley Online Library
… for PMR, various glucocorticoid-related … , of glucocorticoids in some cases. The objective
of this study was to elucidate the efficacy of TCZ monotherapy in the absence of glucocorticoids

Glucocorticoid-resistant polymyalgia rheumatica: pretreatment characteristics and tocilizumab therapy

S Mori, Y Koga - Clinical Rheumatology, 2016 - Springer
… Two patients achieved remission with TCZ monotherapy (… Two patients achieved remission
with TCZ monotherapy (… TCZ as a GC-sparing agent or as monotherapy for PMR patients. The …

Monitoring and long-term management of giant cell arteritis and polymyalgia rheumatica

D Camellino, EL Matteson, F Buttgereit… - Nature Reviews …, 2020 - nature.com
glucocorticoid monotherapy is suggested, whereas in the BSR guidelines discontinuation
of glucocorticoids after 12–18 months is targeted 107,117 . The tapering of glucocorticoids can …