Improving oral absorption via drug-loaded nanocarriers: absorption mechanisms, intestinal models and rational fabrication
MA Shahbazi, HA Santos - Current drug metabolism, 2013 - ingentaconnect.com
… oral absorption prediction. First, we review the mechanisms of drug nanocarrier absorption.
… used as in vitro models to predict intestinal absorption of nanoparticles. Finally, intestinal …
… used as in vitro models to predict intestinal absorption of nanoparticles. Finally, intestinal …
Rational design of oral modified-release drug delivery systems
Y Qiu, PI Lee - Developing solid oral dosage forms, 2017 - Elsevier
… Oral modified release (MR) dosage forms are developed by altering the kinetics and site of
drug release and absorption … , and techniques essential to the rational design of MR delivery …
drug release and absorption … , and techniques essential to the rational design of MR delivery …
Ligand-modified nanocarriers for oral drug delivery: challenges, rational design, and applications
Y Zhang, Y Wang, X Li, D Nie, C Liu, Y Gan - Journal of Controlled Release, 2022 - Elsevier
… Consequently, the targeting capacity, absorption efficiency, and curative effect of oral LMNCs
are … Oral LMNCs fabricated with durable and stable materials are essential to conquer the …
are … Oral LMNCs fabricated with durable and stable materials are essential to conquer the …
Rational design of hybrid nanomicelles integrating mucosal penetration and P-glycoprotein inhibition for efficient oral delivery of paclitaxel
H Lian, Z He, Z Meng - Colloids and Surfaces B: Biointerfaces, 2017 - Elsevier
… a synergistic promotion of drug absorption. Herein, a dual … Hybrid nanomicelles were
rationally fabricated through the … study significantly improved the oral absorption of PTX. Other …
rationally fabricated through the … study significantly improved the oral absorption of PTX. Other …
[HTML][HTML] Rational design of oral drugs targeting mucosa delivery with gut organoid platforms
… microbiota by both Fab-dependent and Fab-independent … models, which describe the
absorption, disposition, and toxicity … to produce fully functional oral drug delivery vehicles (ODDVs…
absorption, disposition, and toxicity … to produce fully functional oral drug delivery vehicles (ODDVs…
Oral drug delivery platforms for biomedical applications
… Therefore, with the advancement of material science and micro-/nano-fabrication techniques…
layer limits their absorption in the GI tract. Therefore, the rational design of oral drug delivery …
layer limits their absorption in the GI tract. Therefore, the rational design of oral drug delivery …
[HTML][HTML] Physical methods for enhancing drug absorption from the gastrointestinal tract
… and 3D printing, have also been explored to conceive sophisticated oral delivery devices.
The high-resolution fabrication offered by these processes not only allows the precise control …
The high-resolution fabrication offered by these processes not only allows the precise control …
Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers
… oral delivery of four types of nutraceuticals, namely fatty acids, bioactive peptides, micronutrients,
and phytochemicals. Factors preventing oral absorption … to improve oral bioavailability …
and phytochemicals. Factors preventing oral absorption … to improve oral bioavailability …
Mechanisms of chitosan-coated poly (lactic-co-glycolic acid) nanoparticles for improving oral absorption of 7-ethyl-10-hydroxycamptothecin
M Guo, WT Rong, J Hou, DF Wang, Y Lu… - …, 2013 - iopscience.iop.org
… accumulation and transport investigations, we speculate rationally that CHI/PLGA NPs
were … In this study, CHI/PLGA NPs were fabricated by the emulsion solvent evaporation (O/W) …
were … In this study, CHI/PLGA NPs were fabricated by the emulsion solvent evaporation (O/W) …
Rationally designed dendritic silica nanoparticles for oral delivery of exenatide
… oral delivery of peptides remains challenging due to the chemical and enzymatic hydrolysis
and poor absorption… Despite these hurdles, the pursuit to develop oral drug delivery systems …
and poor absorption… Despite these hurdles, the pursuit to develop oral drug delivery systems …
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