In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …

Depression is one of the most prevalent and life-threatening forms of mental illnesses,
whereas Alzheimer's disease is a neurodegenerative disorder that affects more than 37 …

Late-life depression is associated with significant cognitive impairment. Meta-analyses
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …

Depression occurs with a high prevalence of up to 50% in patients with Alzheimer's disease
(AD) and increases the caregivers' burden. Depression symptoms can precede clinical …

Major depression (MDD) is a chronic psychiatric condition in which patients often show
increasing cognitive impairment with recurring episodes. Neurodegeneration may play an …

Alzheimer's disease is a neurodegenerative condition affecting millions of people
worldwide. Alzheimer's symptoms include memory loss and cognitive decline …

TGF-β/Smad signalling has been the subject of extensive research due to its role in the cell
cycle and carcinogenesis. Modifications to the TGF-β/Smad signalling pathway have been …

Transforming growth factor-β1 (TGF-β1) is a neurotrophic factor that exerts neuroprotective
effects against β-amyloid-induced neurodegeneration. Recently, a specific impairment of the …

Alzheimer's disease (AD) is a neurodegenerative disorder that affects more than 37 million
people worldwide. Current drugs for AD are only symptomatic, but do not interfere with the …

Alzheimer's disease (AD) is a neurodegenerative disorder that affects about 35 million
people worldwide. Current drugs for AD only treat the symptoms and do not interfere with the …