Strategies for improving the payload of small molecular drugs in polymeric micelles
Y Zhang, T Ren, J Gou, L Zhang, X Tao, B Tian… - Journal of Controlled …, 2017 - Elsevier
In the past few years, substantial efforts have been made in the design and preparation of
polymeric micelles as novel drug delivery vehicles. Typically, polymeric micelles possess a …
polymeric micelles as novel drug delivery vehicles. Typically, polymeric micelles possess a …
Polymeric micelles as drug delivery vehicles
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …
Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs
Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …
the clinical setting. Due to the rising number of compounds having solubility issues, finding …
Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
[HTML][HTML] New advances in biomedical application of polymeric micelles
A Figueiras, C Domingues, I Jarak, AI Santos, A Parra… - Pharmaceutics, 2022 - mdpi.com
In the last decade, nanomedicine has arisen as an emergent area of medicine, which
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …
Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles
Polymeric micelles self-assembled from biodegradable amphiphilic block copolymers have
been proven to be effective drug delivery carriers that reduce the toxicity and enhance the …
been proven to be effective drug delivery carriers that reduce the toxicity and enhance the …
Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle–cell interaction
Importance of the field: Spontaneously constructed from block copolymers in aqueous
media, the polymer micelle has been extensively studied as a potential carrier of poorly …
media, the polymer micelle has been extensively studied as a potential carrier of poorly …
Polymeric micelles: A ray of hope among new drug delivery systems
In this fast-growing nanotechnological drug delivery era the focus is narrowing to real
nanocarriers that can be commercialized to improve human healthcare. Many nanocarriers …
nanocarriers that can be commercialized to improve human healthcare. Many nanocarriers …
Rational design of polymeric micelles for targeted therapeutic delivery
Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
Strategies to improve micelle stability for drug delivery
Micelles have been studied as drug delivery carriers for decades. Their use can potentially
result in high drug accumulation at the target site through the enhanced permeability and …
result in high drug accumulation at the target site through the enhanced permeability and …
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