Iron nutrition and tumor growth: decreased tumor growth in iron-deficient mice

HWL Hann, MW Stahlhut, BS Blumberg - Cancer research, 1988 - AACR
Groups of 15 mice of three different laboratory strains (BALB/c, C3H/He, DBA/2) were fed on
a low iron diet (5 mg iron/kg diet), and three similar groups of 15 mice were maintained on a …

Iron enhances tumor growth. Observation on spontaneous mammary tumors in mice

HWL Hann, MW Stahlhut, H Menduke - Cancer, 1991 - Wiley Online Library
Iron is essential for the growth of all cells, including tumor cells. The authors previously
reported that a variety of transplantable tumors grew faster and larger in mice that were on …

Influence of iron on in vivo proliferation and lethality of L1210 cells

RJ Bergeron, RR Streiff, GT Elliott - The Journal of nutrition, 1985 - Elsevier
The ability of iron to stimulate the growth of L1210 cells both in DBA-2 mice and in cell
culture is evaluated. Although in vitro stimulation is absent, in vivo studies clearly indicate …

Roles of iron in neoplasia: promotion, prevention, and therapy

ED Weinberg - Biological trace element research, 1992 - Springer
Research and clinical observations during the past six decades have shown that: 1. Iron
promotes cancer cell growth; 2. Hosts attempt to withhold or withdraw iron from cancer cells; …

Role of iron in carcinogenesis: cancer as a ferrotoxic disease

S Toyokuni - Cancer science, 2009 - Wiley Online Library
Iron is abundant universally. During the evolutionary processes, humans have selected iron
as a carrier of oxygen inside the body. However, iron works as a double‐edged sword, and …

Iron and neoplasia

ED Weinberg - Biological Trace Element Research, 1981 - Springer
Normal and neoplastic cells (like nonpathogenic and pathogenic microorganisms)
apparently have similar needs and tolerances for iron, but neoplastic cells (like pathogenic …

Promotion of dimethylbenz [a] anthracene-initiated mammary carcinogenesis by iron in female Sprague-Dawley rats.

BA Diwan, KS Kasprzak, LM Anderson - Carcinogenesis, 1997 - academic.oup.com
Iron body-stores and iron dietary intake have been sporadically reported to increase the risk
of cancer in humans. To investigate the effect of iron on the development of mammary …

Iron in neoplastic disease

ED Weinberg - Nutrition and cancer, 1982 - Taylor & Francis
Microbiologists have long believed, and have often demonstrated, that discoveries made in
microbial biochemistry, genetics, nutrition, and physiology can be extrapolated from …

The role of iron in cancer

ED Weinberg - European Journal of Cancer Prevention, 1996 - journals.lww.com
Numerous laboratory and clinical investigations over the past few decades have observed
that one of the dangers of iron is its ability to favour neoplastic cell growth. The metal is …

Iron and the risk of cancer

RG Stevens - Medical oncology and tumor pharmacotherapy, 1990 - Springer
Four epidemiological studies have been performed that are generally consistent with the
hypothesis that increased available body iron stores increase the risk of cancer or of general …