Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review

X Chen, Y Liu, OD Røe, Y Qian, R Guo, L Zhu, Y Yin… - PloS one, 2013 - journals.plos.org
Background Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI),
gefitinib and erlotinib have been tested as maintenance therapy in patients with advanced …

[HTML][HTML] Final overall survival results from a phase III, randomized, placebo-controlled, parallel-group study of gefitinib versus placebo as maintenance therapy in …

H Zhao, Y Fan, S Ma, X Song, B Han, Y Cheng… - Journal of Thoracic …, 2015 - Elsevier
Background The results of the Iressa in NSCLC for maintenance study (NCT00770588; C-
TONG 0804), which compared gefitinib and placebo as maintenance therapy in patients with …

Gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): a multicentre …

L Zhang, S Ma, X Song, B Han, Y Cheng… - The lancet …, 2012 - thelancet.com
Background Maintenance treatment of patients with advanced non-small-cell lung cancer
(NSCLC) without disease progression after first-line chemotherapy is a subject of ongoing …

Maintenance therapy of gefitinib for non-small-cell lung cancer after first-line chemotherapy regardless of epidermal growth factor receptor mutation: a review in …

R Biaoxue, Y Shuanying, L Wei, Z Wei… - … Medical Research and …, 2012 - Taylor & Francis
Purpose: Gefitinib is a well known therapy for non-small-cell lung cancer (NSCLC). The
purpose of this study was to review clinical reports of gefitinib as maintenance therapy after …

Efficacy, tolerability, and biomarker analyses from a phase III, randomized, placebo-controlled, parallel group study of gefitinib as maintenance therapy in patients with …

L Zhang, M Shenglin, X Song, B Han… - Journal of Clinical …, 2011 - ascopubs.org
LBA7511 Background: INFORM (a phase III, randomized, multicenter, parallel group study;
NCT00770588) investigated the efficacy, safety and tolerability of gefitinib (G) vs. placebo …

[HTML][HTML] Re-administration after the failure of gefitinib or erlotinib in patients with advanced non-small cell lung cancer

Z Song, X Yu, C He, B Zhang… - Journal of Thoracic …, 2013 - ncbi.nlm.nih.gov
Objective Few treatment options are available for advanced non-small cell lung cancer
(NSCLC) patients who have failed of gefitinib or erlotinib treatment in second/third-line …

Erlotinib as maintenance therapy in patients with advanced non-small cell lung cancer: a pooled analysis of three randomized trials

F Petrelli, K Borgonovo, M Cabiddu, S Barni - Anti-cancer drugs, 2011 - journals.lww.com
Three randomized trials (SATURN, ATLAS and IFCT-GFPC 0502) have demonstrated that
the oral antiepidermal growth factor receptor tyrosine kinase inhibitor erlotinib can improve …

Comparison of gefitinib versus erlotinib in patients with nonsmall cell lung cancer who failed previous chemotherapy

ST Kim, J Lee, J Kim, YW Won, JM Sun, J Yun… - Cancer, 2010 - Wiley Online Library
BACKGROUND: Gefitinib and erlotinib are commonly used for salvage therapy in patients
with nonsmall cell lung cancer (NSCLC) who have progressed on prior therapies. Although …

Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
Background: The epidermal growth factor receptor tyrosine kinase inhibitors gefitinib and
erlotinib are effective for advanced non-small cell lung cancer (NSCLC). This meta-analysis …

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
Background First-line chemotherapy for advanced non-small-cell lung cancer (NSCLC) is
usually limited to four to six cycles. Maintenance therapy can delay progression and prolong …