[HTML][HTML] Evidence for a latent precursor (p53 signature) that may precede serous endometrial intraepithelial carcinoma

EA Jarboe, ES Pizer, A Miron, N Monte, GL Mutter… - Modern …, 2009 - nature.com
Both serous intraepithelial carcinoma and endometrial glandular dysplasia are associated
with uterine serous carcinoma. Recently a candidate serous cancer precursor containing …

Molecular identification of “latent precancers” for endometrial serous carcinoma in benign-appearing endometrium

X Zhang, SX Liang, L Jia, N Chen, O Fadare… - The American journal of …, 2009 - Elsevier
Alteration of p53 is an early event in the development of endometrial serous carcinoma
(ESC). We have recently identified a group of benign-looking endometria with p53 …

p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

H Tashiro, C Isacson, R Levine… - The American journal …, 1997 - ncbi.nlm.nih.gov
Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial cancer
associated with rapid progression of disease and a poor prognosis. Both USC and its …

[HTML][HTML] Primary sources of pelvic serous cancer in patients with endometrial intraepithelial carcinoma

L Jia, Z Yuan, Y Wang, JM Cragun, B Kong, W Zheng - Modern Pathology, 2015 - Elsevier
Serous endometrial intraepithelial carcinoma is often associated with extrauterine disease. It
is currently unclear where does the extrauterine disease come from. This study addressed …

Characterization of precursor lesions in the endometrium and fallopian tube epithelium of early-stage uterine serous carcinoma

MC Tolcher, EM Swisher, F Medeiros… - International Journal …, 2015 - journals.lww.com
To determine if selected cases of uterine serous carcinoma (USC) arise from tubal rather
than endometrial epithelium. Bilateral fallopian tubes from 38 women with pure USC were …

Early uterine serous carcinoma: clonal origin of extrauterine disease

RN Baergen, CD Warren, C Isacson… - International journal of …, 2001 - journals.lww.com
Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial
carcinoma that is frequently associated with extrauterine disease despite minimal or no …

Does a p53 “wild-type” immunophenotype exclude a diagnosis of endometrial serous carcinoma?

O Fadare, AA Roma, V Parkash, W Zheng… - Advances in …, 2018 - journals.lww.com
An aberrant p53 immunophenotype may be identified in several histotypes of endometrial
carcinoma, and is accordingly recognized to lack diagnostic specificity in and of itself …

Endometrial glandular dysplasia with frequent p53 gene mutation: a genetic evidence supporting its precancer nature for endometrial serous carcinoma

L Jia, Y Liu, X Yi, A Miron, CP Crum, B Kong… - Clinical Cancer …, 2008 - AACR
Abstract Purpose: Endometrial glandular dysplasia (EmGD) has been recently proposed to
be a putative precursor to endometrial serous carcinoma (ESC). The purpose of this study is …

Coexisting intraepithelial serous carcinomas of the endometrium and fallopian tube: frequency and potential significance

EA Jarboe, A Miron, JW Carlson… - International Journal …, 2009 - journals.lww.com
Most serous adenocarcinomas involving both the endometrium and ovary are presumed to
arise in the endometrium. Recently, serous tubal intraepithelial carcinoma (STIC) has been …

A proposed model for endometrial serous carcinogenesis

W Zheng, L Xiang, O Fadare… - The American journal of …, 2011 - journals.lww.com
Endometrial serous carcinomas constitute no more than 10% of endometrial
adenocarcinomas, but frequently present at an advanced stage and have a significantly …