Advances in the development of novel antioxidant therapies as an approach for fetal alcohol syndrome prevention

X Joya, O Garcia‐Algar, J Salat‐Batlle… - … Research Part A …, 2015 - Wiley Online Library
Ethanol is the most common human teratogen, and its consumption during pregnancy can
produce a wide range of abnormalities in infants known as fetal alcohol spectrum disorder …

A review of interventions against fetal alcohol spectrum disorder targeting oxidative stress

Y Zhang, H Wang, Y Li, Y Peng - International Journal of Developmental …, 2018 - Elsevier
Introduction Fetal alcohol spectrum disorder is caused by maternal ethanol exposure; it
causes physical, behavioral, cognitive, and neural impairments (Murawski et al., 2015) …

The role of folic acid and selenium against oxidative damage from ethanol in early life programming: a review

L Ojeda, F Nogales, L Murillo… - Biochemistry and Cell …, 2018 - cdnsciencepub.com
There are disorders in children, covered by the umbrella term “fetal alcohol spectrum
disorder”(FASD), that occur as result of alcohol consumption during pregnancy and …

Antioxidants and fetal protection against ethanol teratogenicity: I. Review of the experimental data and implications to humans

R Cohen-Kerem, G Koren - Neurotoxicology and teratology, 2003 - Elsevier
Ethanol is the most common human teratogen, and heavy drinking during pregnancy can
result in serious adverse outcomes to the fetus. The cellular mechanisms by which ethanol …

Ethanol exposure during development, and brain oxidative stress

J Gil-Mohapel, CD Bianco, PA Cesconetto… - Neuroscience of …, 2019 - Elsevier
Ethanol exposure during pregnancy can produce a variety of central nervous system
abnormalities in the offspring, resulting in a broad spectrum of cognitive and behavioral …

Postnatal nutritional treatment of neurocognitive deficits in fetal alcohol spectrum disorder

A Bastons-Compta, M Astals… - … and Cell Biology, 2018 - cdnsciencepub.com
Ethanol is the most important teratogen agent in humans. Prenatal alcohol exposure can
lead to a wide range of adverse effects, which are broadly termed as fetal alcohol spectrum …

The role of oxidative stress in fetal alcohol spectrum disorders

PS Brocardo, J Gil-Mohapel, BR Christie - Brain research reviews, 2011 - Elsevier
The ingestion of alcohol/ethanol during pregnancy can result in abnormal fetal development
in both humans and a variety of experimental animal models. Depending on the pattern of …

Neurotoxic effects of alcohol and acetaldehyde during embryonic development

R Da Lee, S Mi An, S Sun Kim… - Journal of Toxicology …, 2005 - Taylor & Francis
Alcohol drinking during pregnancy results in abnormal fetal development, including fetal
alcohol syndrome (FAS) in humans and experimental animals. FAS is characterized by two …

An update on fetal alcohol syndrome—pathogenesis, risks, and treatment

KK Gupta, VK Gupta, T Shirasaka - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Alcohol is a well‐established teratogen that can cause variable physical and behavioral
effects on the fetus. The most severe condition in this spectrum of diseases is known as fetal …

The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model

L Long, Y Li, YD Wang, QY He, M Li… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Fetal alcohol spectrum disorder (FASD) is a challenging public health problem.
Previous studies have found an association between FASD and oxidative stress. In the …