With the increasing number of poorly water-soluble compounds in contemporary drug
discovery pipelines, the concept of supersaturation as an effective formulation approach for …

Contemporary pharmaceutical pipelines are often highly populated with poorly water-
soluble drug candidates necessitating novel formulation technologies to provide dosage …

The formulation development for poorly soluble drugs still remains a challenge.
Supersaturating drug delivery systems (SDDS) or drug delivery systems based on …

At present, the majority of APIs synthesized today remain challenging tasks for formulation
development. Many technologies are being utilized or explored for enhancing solubility …

Supersaturation is a promising strategy to improve gastrointestinal absorption of poorly
water-soluble drugs. Supersaturation is a metastable state and therefore dissolved drugs …

Supersaturating drug delivery systems (SDDS) hold the promise of enabling intestinal
absorption for difficult-to-formulate, poorly soluble drug candidates based on a design …

Supersaturating drug delivery systems can enhance the oral bioavailability of poorly soluble
drug compounds. Supersaturation of such compounds has been studied in many different …

Amorphous solid dispersion (ASD) formulations are widely used for delivery of poorly
soluble drugs for dissolution enhancement and bioavailability improvement. When …

An emerging technology subtype that has been adopted by formulators to address low-
solubility issues is the supersaturating drug delivery system; this system is based on the …

Introduction: With the increasing number of poorly water-soluble compounds in drug
discovery pipelines, supersaturating drug delivery systems (SDDS) have attracted increased …