Eradication of the bacterial pathogen, resolution of the local and systemic inflammatory
signs, and recovery of organ function are the main criteria by which antibiotic treatment is …

In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation …

Pulmonary exacerbations have very important consequences in cystic fibrosis (CF), both in
terms of current morbidity as well as implications for long term morbidity and mortality. Even …

Cystic fibrosis (CF) patients suffer typically from bacterial infections of their airways. Whilst
current antibiotic-based treatment of these infections has brought much benefit to patients, it …

BACKGROUND: Several guidelines on infection control and treatment of infection exist for
cystic fibrosis (CF) caregivers, although the extent of implementation is variable. METHODS …

Chronic pulmonary infections contribute significantly to the morbidity and mortality of
patients with CF. The primary pathogens are Pseudomonas aeruginosa (PA) and …

Cystic fibrosis (CF) lung disease is characterized by chronic bacterial infection and an
unremitting inflammatory response, which are responsible for most of CF morbidity and …

People with cystic fibrosis experience bronchopulmonary exacerbations, leading to lung
damage, lung function decline, increased mortality, and a poor health-related quality of life …

Chronic pulmonary infections are a significant cause of morbidity and mortality in patients
with cystic fibrosis. The traditional approach to managing patients with cystic fibrosis is to …

A comprehensive analysis of the airway microbiome in cystic fibrosis (CF) has revealed that
the airways are a reservoir of previously unrecognized but clinically relevant organisms …