Multienzyme‐Mimicking LaCoO3 Nanotrigger for Programming Cancer‐Cell Pyroptosis
K Xu, M Chang, Z Wang, H Yang, Y Jia… - Advanced …, 2023 - Wiley Online Library
Pyroptosis, a distinct paradigm of programmed cell death, is an efficient strategy against
cancer by overcoming resistance to apoptosis. In this study, LaCoO3 (LCO) lanthanide …
cancer by overcoming resistance to apoptosis. In this study, LaCoO3 (LCO) lanthanide …
A review on electrochemical biosensing platform based on layered double hydroxides for small molecule biomarkers determination
The development of layered double hydroxides (LDHs), also known as anionic clays with
uniform distribution of metal ions and facile exchangeability of intercalated anions, are now …
uniform distribution of metal ions and facile exchangeability of intercalated anions, are now …
Accelerating Ce3+/Ce4+ conversion in CeO2 via Mn doping to endow scaffolds with chemodynamic therapy properties
CeO 2 nanozymes have garnered significant attention in chemodynamic therapy due to their
peroxidase-like activity and ability to deplete glutathione. However, their catalytic efficiency …
peroxidase-like activity and ability to deplete glutathione. However, their catalytic efficiency …
Core-shell iron oxide-layered double hydroxide: high electrochemical sensing performance of H2O2 biomarker in live cancer cells with plasma therapeutics
In this work, we develop a new type of multifunctional core-shell nanomaterial by
controllable integration of CuAl layered double hydroxides (LDHs) over the surface of iron …
controllable integration of CuAl layered double hydroxides (LDHs) over the surface of iron …
Nanozyme-based biofuel cell ingeniously coupled with luminol chemiluminescence system through in situ co-reactant generation for dual-signal biosensing
C Wang, Y Wang, J Liu, F Li, P Gai - Analytical Chemistry, 2023 - ACS Publications
Classical luminol-based chemiluminescence (CL) is the process of emitting light enhanced
by the addition of coreactant hydrogen peroxide (H2O2). To address the instability issue of …
by the addition of coreactant hydrogen peroxide (H2O2). To address the instability issue of …
Recent advances in glucose‐oxidase‐based nanocomposites for tumor therapy
M Wang, D Wang, Q Chen, C Li, Z Li, J Lin - Small, 2019 - Wiley Online Library
Glucose oxidase (GOx) can react with intracellular glucose and oxygen (O2) to produce
hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of …
hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of …
Dual‐depletion of intratumoral lactate and ATP with radicals generation for cascade metabolic‐chemodynamic therapy
Increasing evidence has demonstrated that lactate and adenosine triphosphate (ATP) both
play important roles in regulating abnormal metabolism in the tumor microenvironment …
play important roles in regulating abnormal metabolism in the tumor microenvironment …
Targeting lactate-related cell cycle activities for cancer therapy
J Lin, G Liu, L Chen, HF Kwok, Y Lin - Seminars in cancer biology, 2022 - Elsevier
Lactate has long been considered as a metabolic by-product of aerobic glycolysis for
cancer. However, more and more studies have shown that lactate can regulate cancer …
cancer. However, more and more studies have shown that lactate can regulate cancer …
A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis
Recently, lactate has been considered as an alternative direct energy substance to glucose
for tumor proliferation and metastasis. Meanwhile, mitochondria, as important energy …
for tumor proliferation and metastasis. Meanwhile, mitochondria, as important energy …
Biomimetic Hybrid Nanozymes with Self-Supplied H+ and Accelerated O2 Generation for Enhanced Starvation and Photodynamic Therapy against Hypoxic Tumors
Nanozymes as artificial enzymes that mimicked natural enzyme-like activities have received
great attention in cancer diagnosis and therapy. Biomimetic nanozymes require more …
great attention in cancer diagnosis and therapy. Biomimetic nanozymes require more …