Multienzyme‐Mimicking LaCoO3 Nanotrigger for Programming Cancer‐Cell Pyroptosis

K Xu, M Chang, Z Wang, H Yang, Y Jia… - Advanced …, 2023 - Wiley Online Library
Pyroptosis, a distinct paradigm of programmed cell death, is an efficient strategy against
cancer by overcoming resistance to apoptosis. In this study, LaCoO3 (LCO) lanthanide …

A review on electrochemical biosensing platform based on layered double hydroxides for small molecule biomarkers determination

M Asif, A Aziz, M Azeem, Z Wang, G Ashraf… - Advances in colloid and …, 2018 - Elsevier
The development of layered double hydroxides (LDHs), also known as anionic clays with
uniform distribution of metal ions and facile exchangeability of intercalated anions, are now …

Accelerating Ce3+/Ce4+ conversion in CeO2 via Mn doping to endow scaffolds with chemodynamic therapy properties

C Shuai, K Wang, S Peng, J Zan, J Xiao, S Hu… - Surfaces and …, 2024 - Elsevier
CeO 2 nanozymes have garnered significant attention in chemodynamic therapy due to their
peroxidase-like activity and ability to deplete glutathione. However, their catalytic efficiency …

Core-shell iron oxide-layered double hydroxide: high electrochemical sensing performance of H2O2 biomarker in live cancer cells with plasma therapeutics

M Asif, H Liu, A Aziz, H Wang, Z Wang, M Ajmal… - Biosensors and …, 2017 - Elsevier
In this work, we develop a new type of multifunctional core-shell nanomaterial by
controllable integration of CuAl layered double hydroxides (LDHs) over the surface of iron …

Nanozyme-based biofuel cell ingeniously coupled with luminol chemiluminescence system through in situ co-reactant generation for dual-signal biosensing

C Wang, Y Wang, J Liu, F Li, P Gai - Analytical Chemistry, 2023 - ACS Publications
Classical luminol-based chemiluminescence (CL) is the process of emitting light enhanced
by the addition of coreactant hydrogen peroxide (H2O2). To address the instability issue of …

Recent advances in glucose‐oxidase‐based nanocomposites for tumor therapy

M Wang, D Wang, Q Chen, C Li, Z Li, J Lin - Small, 2019 - Wiley Online Library
Glucose oxidase (GOx) can react with intracellular glucose and oxygen (O2) to produce
hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of …

Dual‐depletion of intratumoral lactate and ATP with radicals generation for cascade metabolic‐chemodynamic therapy

F Tian, S Wang, K Shi, X Zhong, Y Gu, Y Fan… - Advanced …, 2021 - Wiley Online Library
Increasing evidence has demonstrated that lactate and adenosine triphosphate (ATP) both
play important roles in regulating abnormal metabolism in the tumor microenvironment …

Targeting lactate-related cell cycle activities for cancer therapy

J Lin, G Liu, L Chen, HF Kwok, Y Lin - Seminars in cancer biology, 2022 - Elsevier
Lactate has long been considered as a metabolic by-product of aerobic glycolysis for
cancer. However, more and more studies have shown that lactate can regulate cancer …

A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis

H Tian, L Zhou, Y Wang, EC Nice, C Huang… - Journal of Controlled …, 2022 - Elsevier
Recently, lactate has been considered as an alternative direct energy substance to glucose
for tumor proliferation and metastasis. Meanwhile, mitochondria, as important energy …

Biomimetic Hybrid Nanozymes with Self-Supplied H+ and Accelerated O2 Generation for Enhanced Starvation and Photodynamic Therapy against Hypoxic Tumors

X Yang, Y Yang, F Gao, JJ Wei, CG Qian, MJ Sun - Nano letters, 2019 - ACS Publications
Nanozymes as artificial enzymes that mimicked natural enzyme-like activities have received
great attention in cancer diagnosis and therapy. Biomimetic nanozymes require more …