Tumor‐specific drug release and reactive oxygen species generation for cancer chemo/chemodynamic combination therapy

S Wang, Z Wang, G Yu, Z Zhou, O Jacobson… - Advanced …, 2019 - Wiley Online Library
The combination of chemotherapeutic drugs and reactive oxygen species (ROS) is a
promising strategy to achieve improved anticancer effect. Herein, a nanomedicine …

A well-thought-out sensory protocol for screening of oxygen reactive species released from cancer cells

MY Emran, SA El-Safty, MA Shenashen… - Sensors and Actuators B …, 2019 - Elsevier
Facilely constructed metal nanoparticles with highly active sites, high economic impact, and
stable electrocatalysts are crucial to developed sensory protocol for oxygen reactive species …

A nonenzymatic hydrogen peroxide electrochemical sensing and application in cancer diagnosis

Y Yu, J Peng, M Pan, Y Ming, Y Li, L Yuan… - Small …, 2021 - Wiley Online Library
The diagnosis of malignant tumors is essential for informing clinical decisions regarding
therapeutic options. Current imaging and pathological diagnostic methods do not provide …

Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma

G Lu, X Wang, F Li, S Wang, J Zhao, J Wang… - Nature …, 2022 - nature.com
Glioblastoma multiforme (GBM) is an aggressive brain cancer with a poor prognosis and few
treatment options. Here, building on the observation of elevated lactate (LA) in resected …

Recent Advances in Electrochemical Sensing of Hydrogen Peroxide (H2O2) Released from Cancer Cells

T Ahmad, A Iqbal, SA Halim, J Uddin, A Khan… - Nanomaterials, 2022 - mdpi.com
Cancer is by far the most common cause of death worldwide. There are more than 200 types
of cancer known hitherto depending upon the origin and type. Early diagnosis of cancer …

Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy

M Ye, Y Song, S Pan, M Chu, ZW Wang… - Pharmacology & …, 2020 - Elsevier
The lysyl oxidase (LOX) family is comprised of LOX and four LOX-like proteins (LOXL1,
LOXL2, LOXL3, and LOXL4), and mainly functions in the remodeling of extracellular matrix …

Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors

X Teng, L Qi, T Liu, L Li, C Lu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Reactive oxygen species (ROS), well-known as the highly reactive small molecules, play an
important role in physiological and pathogenic events. Therefore, the detection of ROS …

Advanced cobalt-ferrite layered double hydroxides sandwich-structured nanozymes for ROS-bloomed tumor therapy

S Li, X Zhao, H Ding, J Chang, X Qin, F He… - Chemical Engineering …, 2023 - Elsevier
Artificial-engineered nanozymes show great promise for improving cancer therapeutic
outcomes. Herein, we elaborately designed the advanced cobalt-ferrite layered double …

Nanoclustered cascaded enzymes for targeted tumor starvation and deoxygenation-activated chemotherapy without systemic toxicity

Y Ma, Y Zhao, NK Bejjanki, X Tang, W Jiang, J Dou… - ACS …, 2019 - ACS Publications
Intratumoral glucose depletion-induced cancer starvation represents an important strategy
for anticancer therapy, but it is often limited by systemic toxicity, nonspecificity, and adaptive …

Design of an enzyme-mimicking NiO@ Au nanocomposite for the sensitive electrochemical detection of lactic acid in human serum and urine

G Maduraiveeran, A Chen - Electrochimica Acta, 2021 - Elsevier
Detection of lactic acid (LA) in biological systems is required for medical diagnostics and the
management of numerous medical conditions due to its key active metabolic role in the …