Lactate, as the most abundant component with concentrations of 4–40 mm in tumors,
contributes to the regulation of metabolic pathways, angiogenesis, and immunosuppression …

Nanozymes have brought enormous opportunities for disease theranostics. Here, a self-
enhanced catalytic nanocrystal based on a bismuth–manganese core–shell nanoflower …

Anticancer drugs are not purely effective because of their toxicity, side effects, high cost,
inaccessibility, and associated resistance. On the other hand, cancer is a complex public …

The excessive lactate in the tumor microenvironment always leads to poor therapeutic
outcomes of chemotherapy. In this study, a self-driven bioreactor (defined as SO@ MDH …

A novel luminol electrochemiluminescence (ECL) sensing platform was developed based
on the closed indium tin oxide bipolar electrode (ITO BPE) for detecting the biomarkers of …

Excess reactive oxygen species (ROS) have been proved to damage cancer cells efficiently.
ROS overproduction is thus greatly desirable for cancer therapy. To date, ROS production is …

To immobilize laccase (Lac) from Trametes versicolor that shows its maximum enzymatic
activity in acidic aqueous solutions, the biopolymer chitosan (CS) was chemically modified …

Gallic acid (GA) holds great potential in anti-cancer, anti-mutagenesis and as antioxidant.
Thus its quantification is essential for quality control of GA-based drugs and health-care …

As an increased product of high-rate aerobic glycolysis in tumors, lactate could regulate the
immunosuppressive tumor microenvironment (TME). A PEG-CDM surface modified, GSH …

Lactate has been observed to fuel TCA cycle and is associated with cancer progression in
human lung cancer, the leading cause of cancer deaths worldwide, but the effect of lactate …