Glioblastoma, also known as glioblastoma multiforme, is the most aggressive brain tumor in
adults. Despite the huge advance in developing novel therapeutic strategies for patients with …

Glioma originates in the central nervous system and is classified based on both histological
features and molecular genetic characteristics. Long non-coding RNAs (lncRNAs) are …

Gliomas are a primary types of intracranial malignancies and are characterized by a poor
prognosis due to aggressive recurrence profiles. Temozolomide (TMZ) is an auxiliary …

As the most common primary tumour of the central nervous system, gliomas have a high
recurrence rate after surgical resection and are resistant to chemotherapy, particularly high …

Temozolomide (TMZ) and radiation therapy combination for glioblastoma (GB) patients has
been considered as the most effective therapy after surgical procedure. However, the overall …

Non-coding RNAs (ncRNAs) have been recognized as pivotal regulators of transcriptional
and post-transcriptional gene modulation, exerting a profound influence on a diverse array …

Long non‐coding RNAs (lncRNAs), a class of long RNAs, are longer than 200 nucleotides in
length but lack protein‐coding capacity. LncRNAs, as critical genomic regulators, are …

Background Malignant tumors have become the most dangerous disease in recent years.
Chemotherapy is the most effective treatment for this disease; however, the problem of drug …

Glioma is the most prevalent invasive primary tumor of the central nervous system. Glioma
cells can spread and infiltrate into normal surrounding brain tissues. Despite the standard …

The presence or emergence of chemoresistance in tumor cells is a major burden in cancer
therapy. While drug resistance is a multifactorial phenomenon arising from altered …