Clonal hematopoiesis (CH) is a clonally expanded population of hematopoietic stem cells
carrying somatic mutations that differentiate through multilineage hematopoiesis to form …

As individuals age, their hematopoietic stem cells can sporadically acquire genetic
mutations, known as clonal hematopoiesis. Although most of these genomic aberrations are …

Some random mutations can confer a selective advantage to a hematopoietic stem cell. As a
result, mutated hematopoietic stem cells can give rise to a significant proportion of mutated …

Introduction: Clonal hematopoiesis (CH) denotes somatic mutations in genes related to
myeloid neoplasms present at any variant allele frequency (VAF). Clonal hematopoiesis …

Importance Clonal hematopoiesis (CH) has been recently described as a novel driver for
cancer and cardiovascular disease (CVD). Clonal hematopoiesis is a common, age …

Hematopoietic stem cells (HSCs) are polyfunctional, regenerating all blood cells via
hematopoiesis throughout life. Clonal hematopoiesis (CH) is said to occur when a …

Clonal hematopoiesis (CH) is an entity hallmarked by skewed hematopoiesis with persistent
overrepresentation of cells from a common stem/progenitor lineage harboring single …

Clonal hematopoiesis (CH) is a prevalent condition that results from somatic mutations in
hematopoietic stem cells. When these mutations occur in “driver” genes, they can potentially …

Abstract Purpose of Review Clonal hematopoiesis (CH) is an age-dependent process
detectable using advanced sequencing technologies and is associated with multiple …

A number of recent epidemiological studies have associated the clonal expansion of
hematopoietic cells, a process referred to as clonal hematopoiesis, with increased mortality …