Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route

A Sharabi, E Cohen, J Sulkes… - British journal of clinical …, 2003 - Wiley Online Library
Aims To compare the efficacy of sublingual and oral administration of 500 µg of cobalamin in
subjects with cobalamin deficiency. Materials and results Thirty subjects with low serum …

An update on cobalamin deficiency in adults

N Dali-Youcef, E Andrès - QJM: An International Journal of …, 2009 - academic.oup.com
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (> 65 years of age),
but is often unrecognized because of its subtle clinical manifestations; although they can be …

Efficacy of oral cobalamin (vitamin B12) therapy

E Andrès, H Fothergill, M Mecili - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Cobalamin (vitamin B12) deficiency is particularly common in the
elderly (> 15%). Management of cobalamin deficiency with cobalamin injections is well …

Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial

B Favrat, P Vaucher, L Herzig, B Burnand, G Ali… - BMC family …, 2011 - Springer
Background Evidence regarding the effectiveness of oral vitamin B12 in patients with serum
vitamin B12 levels between 125-200 pM/l is lacking. We compared the effectiveness of one …

Treatment of Vitamin B12–Deficiency Anemia: Oral versus Parenteral Therapy

LA Lane, C Rojas-Fernandez - Annals of Pharmacotherapy, 2002 - journals.sagepub.com
OBJECTIVE: To evaluate the use of oral cyanocobalamin therapy in the treatment of
cobalamin (vitamin B12)–deficient anemia. DATA SOURCES: Primary and review articles …

Efficacy of short‐term oral cobalamin therapy for the treatment of cobalamin deficiencies related to food‐cobalamin malabsorption: a study of 30 patients

E Andres, G Kaltenbach, E Noel… - Clinical & Laboratory …, 2003 - Wiley Online Library
Background: It has been suggested that oral cobalamin (vitamin B12) therapy may be an
effective therapy for treating cobalamin deficiencies related to food‐cobalamin …

Oral cobalamin (vitamin B12) treatment. An update

E Andrès, N Dali‐Youcef, T Vogel… - … journal of laboratory …, 2009 - Wiley Online Library
The objective of this review was to evaluate oral cobalamin (vitamin B12) therapy in adult
and elderly patients, from the perspective of a hematologist. PubMed was systematically …

Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a …

MC Castelli, K Friedman, J Sherry, K Brazzillo… - Clinical …, 2011 - Elsevier
Background Vitamin B 12 deficiency is routinely treated with parenteral dosing and less
often with high-dose oral vitamin B 12. Oral vitamin B 12 formulations have low …

The pathophysiology of elevated vitamin B12 in clinical practice

E Andrès, K Serraj, J Zhu… - QJM: An International …, 2013 - academic.oup.com
Hypercobalaminemia (high serum vitamin B12 levels) is a frequent and underestimated
anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, reflecting a …

Oral vitamin B12 can change our practice

E Nyholm, P Turpin, D Swain… - Postgraduate …, 2003 - academic.oup.com
Oral vitamin B12 can provide an effective alternative to intramuscular injections, so giving
patients a choice and reducing costs in primary care. This study investigated the …