Clonal hematopoiesis (CH) of indeterminate potential (CHIP), defined as the presence of a
somatic mutation in the peripheral blood at a variant allele frequency (VAF)≥ 2%, affects at …

Recent genome‐wide studies have revealed that aging or chronic inflammation can cause
clonal expansion of cells in normal tissues. Clonal hematopoiesis has been the most …

Clonally restricted hematopoiesis is a common aging-associated biological state that
predisposes to subsequent development of a hematological malignancy or cardiovascular …

Clonal hematopoiesis of indeterminate potential (CHIP) describes a widespread expansion
of genetically variant hematopoietic cells that increases exponentially with age and is …

Acquired genetic or cytogenetic alterations in a blood stem cell that confer clonal fitness
promote its relative expansion leading to clonal hematopoiesis (CH). Despite a largely intact …

Clonal hematopoiesis (CH) is described as the outsized contribution of expanded clones of
hematopoietic stem and progenitor cells (HSPCs) to blood cell production. The prevalence …

Chronic obstructive pulmonary disease (COPD) is associated with age and smoking, but
other determinants of the disease are incompletely understood. Clonal hematopoiesis of …

Clonal hematopoiesis of indeterminate potential (CHIP), also referred to as aging-related
clonal hematopoiesis, is defined as an asymptomatic clonal expansion of mutant mature …

Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by the expansion of
hematopoietic cells harboring leukemia-associated somatic mutations in otherwise healthy …

Clonal hematopoiesis (CH) describes an asymptomatic expansion of blood cells descended
from a single hematopoietic stem cell. Recent studies have shown that CH increases in …