Effect of obesity, dyslipidemia, and diabetes on trastuzumab-related cardiotoxicity in breast cancer

P Kosalka, C Johnson, M Turek, J Sulpher, A Law… - Current …, 2019 - mdpi.com
Background: Clinical trials have demonstrated an increased risk of cardiotoxicity in patients
with breast cancer (BCA) receiving trastuzumab-based therapy. Diabetes, dyslipidemia, and …

Incidence and identification of risk factors for trastuzumab-induced cardiotoxicity in breast cancer patients: an audit of a single “real-world” setting

GH Tang, SA Acuna, L Sevick, AT Yan… - Medical Oncology, 2017 - Springer
Management of human epidermal growth factor receptor-2-positive (HER2+) breast cancer
patients includes the combination of adjuvant chemotherapy and trastuzumab. A meta …

Risk factors for developing cardiotoxicity of trastuzumab in breast cancer patients: an observational single-centre study

M Gunaldi, BB Duman, CU Afsar… - Journal of Oncology …, 2016 - journals.sagepub.com
Background Trastuzumab is a recombinant humanized monoclonal antibody used to treat
human epidermal growth factor receptor 2 positive breast cancer, with recognized …

Risk factors of trastuzumab-induced cardiotoxicity in breast cancer: a meta-analysis

Z Jawa, RM Perez, L Garlie, M Singh, R Qamar… - Medicine, 2016 - journals.lww.com
Background: Trastuzumab targets the human epidermal growth factor receptor 2 oncogene
and in combination with first-line therapy results in significantly improved survival outcomes …

Conventional cardiac risk factors associated with trastuzumab-induced cardiotoxicity in breast cancer: Systematic review and meta-analysis

G Koulaouzidis, AE Yung, DE Yung… - Current Problems in …, 2021 - Elsevier
Background: Trastuzumab has had a major impact on the treatment of human epidermal
growth factor receptor 2 (HER2) positive breast cancer patients. However, it is associated …

Incidence, diagnosis, and treatment of cardiac toxicity from trastuzumab in patients with breast cancer

S Nowsheen, PV Viscuse, CC O'Sullivan… - Current breast cancer …, 2017 - Springer
Abstract Purpose of Review Treatment with trastuzumab is a cornerstone of human
epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer treatment, but …

Trastuzumab-induced cardiotoxicity and its risk factors in real-world setting of breast cancer patients

T Moilanen, A Jokimäki, O Tenhunen… - Journal of Cancer …, 2018 - Springer
Purpose Cardiotoxicity is the most important side effect of trastuzumab treatment. Heart
function monitoring is recommended during the treatment which has led to growing use of …

Trastuzumab-induced cardiotoxicity: testing a clinical risk score in a real-world cardio-oncology population

M Rushton, C Johnson, S Dent - Current Oncology, 2017 - mdpi.com
Background: Trastuzumab has improved survival for women with HER2-positive breast
cancer, but its use is associated with an increased risk of cardiotoxicity. With increased …

Risk of cardiac dysfunction with trastuzumab in breast cancer patients: a meta-analysis

T Chen, T Xu, Y Li, C Liang, J Chen, Y Lu, Z Wu… - Cancer treatment …, 2011 - Elsevier
BACKGROUND: Trastuzumab is used widely for the treatment of early and advanced breast
cancer. However, concerns have arisen regarding its cardiac toxicity. We did a systematic …

Risks of trastuzumab‐related cardiotoxicity in breast cancer patients in Taiwan

WT Chang, PW Chen, HW Lin, SH Lin… - ESC heart failure, 2021 - Wiley Online Library
Abstract Aims In contrast to Western patients with breast cancer, Asian patients are relatively
younger at diagnosis, and most are free from traditional cardiovascular risk factors. Despite …