COVID-19 and preexisting comorbidities: risks, synergies, and clinical outcomes

B Bigdelou, MR Sepand, S Najafikhoshnoo… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …

Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider

A Najm, A Alunno, X Mariette, B Terrier, G De Marco… - RMD open, 2021 - rmdopen.bmj.com
Background The SARS-CoV-2 pandemic is a global health problem. Beside the specific
pathogenic effect of SARS-CoV-2, incompletely understood deleterious and aberrant host …

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

Looking for pathways related to COVID-19: confirmation of pathogenic mechanisms by SARS-CoV-2–host interactome

F Messina, E Giombini, C Montaldo, AA Sharma… - Cell Death & …, 2021 - nature.com
In the last months, many studies have clearly described several mechanisms of SARS-CoV-
2 infection at cell and tissue level, but the mechanisms of interaction between host and …

Risk factors for adverse outcomes of COVID-19 patients: Possible basis for diverse responses to the novel coronavirus SARS-CoV-2

M Ghaebi, S Tahmasebi, M Jozghorbani, A Sadeghi… - Life sciences, 2021 - Elsevier
Abstract Severe coronavirus disease 2019 (COVID-19) caused by the Severe Acute
Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is characterized by an unpredictable …

[PDF][PDF] Long-COVID and post-COVID health complications: an up-to-date review on clinical conditions and their possible molecular mechanisms. Viruses. 2021; 13 (4) …

B Silva Andrade, S Siqueira… - DOI: 10.32364/2587 …, 2021 - researchgate.net
The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-
term care of COVID-19 survivors. It is thus imperative to study post-COVID (ie, short-term) …

Biomarkers during COVID-19: mechanisms of change and implications for patient outcomes

CH Chen, SW Lin, CF Shen, KS Hsieh, CM Cheng - Diagnostics, 2022 - mdpi.com
As the COVID-19 (Coronavirus disease 19) pandemic spreads worldwide, the massive
numbers of COVID-19 patients have created a considerable healthcare burden for every …

A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?

B Shakaib, T Zohra, A Ikram, MB Shakaib, A Ali… - Virology journal, 2021 - Springer
Since its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic,
affecting more than 52 million people and causing more than 1 million mortalities globally till …

Inflammation triggered by SARS-CoV-2 and ACE2 augment drives multiple organ failure of severe COVID-19: molecular mechanisms and implications

M Iwasaki, J Saito, H Zhao, A Sakamoto, K Hirota, D Ma - Inflammation, 2021 - Springer
The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …

[HTML][HTML] COVID-19 signalome: Pathways for SARS-CoV-2 infection and impact on COVID-19 associated comorbidity

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular …, 2023 - Elsevier
The COVID-19 pandemic has been the focus of research the past two years. The major
breakthrough was made by discovering pathways related to SARS-CoV-2 infection through …