ACE2 interaction networks in COVID-19: a physiological framework for prediction of outcome in patients with cardiovascular risk factors

Z Wicik, C Eyileten, D Jakubik, SN Simões… - Journal of clinical …, 2020 - mdpi.com
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
(coronavirus disease 2019; COVID-19) is associated with adverse outcomes in patients with …

Identification of PBMC-based molecular signature associational with COVID-19 disease severity

H Shaath, NM Alajez - Heliyon, 2021 - cell.com
The longevity of COVID-19 as a global pandemic, and the devastating effects it has had on
certain subsets of individuals thus far has highlighted the importance of identifying blood …

Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study

SK Byeon, AK Madugundu, K Garapati… - The Lancet Digital …, 2022 - thelancet.com
Background COVID-19 is a multi-system disorder with high variability in clinical outcomes
among patients who are admitted to hospital. Although some cytokines such as interleukin …

Host/genetic factors associated with COVID-19 call for precision medicine

AR Thierry - Precision Clinical Medicine, 2020 - academic.oup.com
If the current rate of infection are to be better managed, and future waves of infection kept at
bay, it is absolutely necessary that the conditions and mechanisms of exposure to Severe …

Long-COVID and post-COVID health complications: an up-to-date review on clinical conditions and their possible molecular mechanisms

B Silva Andrade, S Siqueira, WR de Assis Soares… - Viruses, 2021 - mdpi.com
The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-
term care of COVID-19 survivors. It is thus imperative to study post-COVID (ie, short-term) …

Informing the public health response to COVID-19: a systematic review of risk factors for disease, severity, and mortality

M Flook, C Jackson, E Vasileiou, CR Simpson… - BMC infectious …, 2021 - Springer
Abstract Background Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2) has
challenged public health agencies globally. In order to effectively target government …

Identification of SARS-CoV-2–specific immune alterations in acutely ill patients

RM Rebillard, M Charabati, C Grasmuck… - The Journal of …, 2021 - Am Soc Clin Investig
Dysregulated immune profiles have been described in symptomatic patients infected with
SARS-CoV-2. Whether the reported immune alterations are specific to SARS-CoV-2 …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes

Y Li, AM Schneider, A Mehta… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND SARS-CoV-2 plasma viremia has been associated with severe disease and
death in COVID-19 in small-scale cohort studies. The mechanisms behind this association …