White matter damage and cognitive impairment after traumatic brain injury

KM Kinnunen, R Greenwood, JH Powell, R Leech… - Brain, 2011 - academic.oup.com
White matter disruption is an important determinant of cognitive impairment after brain injury,
but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor …

A multiscale tissue assessment in a rat model of mild traumatic brain injury

I San Martín Molina, M Fratini, G Campi… - … of Neuropathology & …, 2023 - academic.oup.com
Diffusion tensor imaging (DTI) has demonstrated the potential to assess the pathophysiology
of mild traumatic brain injury (mTBI) but correlations of DTI findings and pathological …

Individual prediction of white matter injury following traumatic brain injury

PJ Hellyer, R Leech, TE Ham, V Bonnelle… - Annals of …, 2013 - Wiley Online Library
Objective Traumatic brain injury (TBI) often results in traumatic axonal injury (TAI). This can
be difficult to identify using conventional imaging. Diffusion tensor imaging (DTI) offers a …

Diffusion tensor imaging of traumatic brain injury review: implications for neurorehabilitation

GT Voelbel, HM Genova, ND Chiaravalotti… - …, 2012 - content.iospress.com
Diffusion tensor imaging (DTI) has widely been used to investigate the microstructural
damage of white matter tracts that occur in individuals with traumatic brain injury (TBI). In the …

Characterization of chronic axonal degeneration using diffusion tensor imaging in canine spinal cord injury: a quantitative analysis of diffusion tensor imaging …

H Yoon, J Kim, WJ Moon, SS Nahm, J Zhao… - Journal of …, 2017 - liebertpub.com
Diffusion tensor imaging (DTI) is more sensitive than conventional magnetic resonance
imaging (MRI) for the identification of axonal degeneration. However, no study to date has …

Magnetic resonance imaging of diffuse axonal injury: quantitative assessment of white matter lesion volume

CMDL Plata, A Ardelean, D Koovakkattu… - Journal of …, 2007 - liebertpub.com
Diffuse axonal injury (DAI) is a common mechanism of traumatic brain injury (TBI) for which
there is no well-accepted anatomic measures of injury severity. The present study aims to …

Longitudinal diffusion tensor imaging and neuropsychological correlates in traumatic brain injury patients

KD Farbota, BB Bendlin, AL Alexander… - Frontiers in human …, 2012 - frontiersin.org
Traumatic brain injury (TBI) often involves focal cortical injury and white matter (WM)
damage that can be measured shortly after injury. Additionally, slowly evolving WM change …

Dynamic changes in diffusion measures improve sensitivity in identifying patients with mild traumatic brain injury

AW Thomas, R Watts, CG Filippi, JP Nickerson… - PLoS …, 2017 - journals.plos.org
The goal of this study was to investigate patterns of axonal injury in the first week after mild
traumatic brain injury (mTBI). We performed a prospective cohort study of 20 patients …

Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury

JH Kim, DN Loy, HF Liang, K Trinkaus… - … in Medicine: An …, 2007 - Wiley Online Library
We examined in vivo measurements of directional diffusivity derived from diffusion tensor
imaging (DTI) to study the evolution of ventrolateral white matter (VWM) changes following …

Serum assessment of traumatic axonal injury: the correlation of GFAP, t-Tau, UCH-L1, and NfL levels with diffusion tensor imaging metrics and its prognosis utility

AM Castaño-Leon, CS Carabias, A Hilario… - Journal of …, 2022 - thejns.org
OBJECTIVE Diagnosis of traumatic axonal injury (TAI) is challenging because of its
underestimation by conventional MRI and the technical requirements associated with the …