Plant-derived triterpenoids as potential antineoplastic agents

WN Setzer, MC Setzer - Mini reviews in medicinal chemistry, 2003 - ingentaconnect.com
Man has relied on plants as a source of medicinal agents for centuries. Today, with the
specter of antibiotic resistance, emerging infectious diseases, and cancers, phytochemicals …

Natural product triterpenoids and their semi-synthetic derivatives with potential anticancer activity

Y Ren, AD Kinghorn - Planta Medica, 2019 - thieme-connect.com
Triterpenoids are distributed widely in higher plants and are of interest because of their
structural diversity and broad range of bioactivities. In particular, there is a very large …

Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy

MN Laszczyk - Planta medica, 2009 - thieme-connect.com
Today cancer treatment is not only a question of eliminating cancer cells by induction of cell
death. New therapeutic strategies also include targeting the tumour microenvironment …

Triterpenoids for cancer prevention and treatment: current status and future prospects

J MR Patlolla, CV Rao - Current pharmaceutical biotechnology, 2012 - ingentaconnect.com
Triterpenoids are ubiquitous in the plant kingdom. Recent evidences support the beneficial
effects of naturallyoccurring triterpenoids against several types of human diseases, including …

Triterpenoids as new promising anticancer drugs

A Petronelli, G Pannitteri, U Testa - Anti-cancer drugs, 2009 - journals.lww.com
Triterpenoids are structurally diverse organic compounds, characterized by a basic
backbone modified in multiple ways, allowing the formation of more than 20 000 naturally …

Selected plant triterpenoids and their amide derivatives in cancer treatment: A review

Z Özdemir, Z Wimmer - Phytochemistry, 2022 - Elsevier
Medicinal plants have been used to treat different diseases throughout the human history
namely in traditional medicine. Most of the plants mentioned in this review article belong …

Anticancer activity of monoterpenes: A systematic review

BIM Silva, EA Nascimento, CJ Silva, TG Silva… - Molecular Biology …, 2021 - Springer
Secondary metabolites have been recognized for centuries as medicinal agents, in
particular monoterpenes which have been the target of research in the discovery of …

A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species

D Kemboi, X Peter, M Langat, J Tembu - Molecules, 2020 - mdpi.com
The genus Euphorbia is one of the largest genera in the spurge family, with diversity in
range, distribution, and morphology. The plant species in this genus are widely used in …

[PDF][PDF] Multidirectional effects of triterpene saponins on cancer cells: mini-review of in vitro studies

P Koczurkiewicz, J Czyż, I Podolak, K Wójcik-Pszczoła… - 2015 - ruj.uj.edu.pl
Triterpene saponins (saponosides) are found in a variety of higher plants and display a wide
range of pharmacological activities, including expectorant, anti-inflamatory, vasoprotective …

Triterpenoids of marine origin as anti-cancer agents

YX Li, SWA Himaya, SK Kim - Molecules, 2013 - mdpi.com
Triterpenoids are the most abundant secondary metabolites present in marine organisms,
such as marine sponges, sea cucumbers, marine algae and marine-derived fungi. A large …