Introduction: Silica materials, in particular mesoporous silicas, have demonstrated excellent
properties to enhance the oral bioavailability of poorly water-soluble drugs. Current research …

Porous silica-based drug delivery systems have shown considerable promise for improving
the oral delivery of poorly water-soluble drugs. More specifically, micro-and meso-porous …

Due to the high number of poorly water-soluble active pharmaceutical ingredients, oral drug
delivery development has become challenging. One of the strategies to enhance drug …

New approaches in pharmaceutical chemistry have resulted in more complex drug
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …

Among the many methods available for solubility enhancement, mesoporous carriers are
generating significant industrial interest. Owing to the spatial confinement of drug molecules …

Loading a poorly water-soluble drug onto a high surface area carrier such as mesoporous
silica (SBA-15) can increase the drug's dissolution rate and oral bioavailability. The loading …

Mesoporous silicas are currently widely studied carrier matrices in drug delivery
applications. Surface functionalization of the silica is often employed in order to enhance the …

Ordered mesoporous silica materials have shown great potential as oral drug delivery
systems for poorly soluble drugs. However, the ability of these delivery systems to generate …

In the last twenty years mesoporous materials (eg, silica, silicon, and to a lesser extent
titanium) have been extensively investigated as possible carriers for controlled drug delivery …

Matrix degradation has a major impact on the release kinetics of drug delivery systems.
Regarding ordered mesoporous silica materials for biomedical applications, their dissolution …