Converged avenues: depression and Alzheimer's disease–shared pathophysiology and novel therapeutics
S Bajaj, R Mahesh - Molecular Biology Reports, 2024 - Springer
Depression, a highly prevalent disorder affecting over 280 million people worldwide, is
comorbid with many neurological disorders, particularly Alzheimer's disease (AD) …
comorbid with many neurological disorders, particularly Alzheimer's disease (AD) …
The putative neurodegenerative links between depression and Alzheimer's disease
Alzheimer's disease (AD) is the leading neurodegenerative cause of dementia in the elderly.
Thus far, there is no curative treatment for this devastating condition, thereby creating …
Thus far, there is no curative treatment for this devastating condition, thereby creating …
Depression and Alzheimer's disease: neurobiological links and common pharmacological targets
Depression is one of the most prevalent and life-threatening forms of mental illnesses,
whereas Alzheimer's disease is a neurodegenerative disorder that affects more than 37 …
whereas Alzheimer's disease is a neurodegenerative disorder that affects more than 37 …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
[HTML][HTML] Pharmacological treatment of depression in Alzheimer's disease: a challenging task
Besides the memory impairment, Alzheimer's disease (AD) is often complicated by
neuropsychiatric symptoms also known as behavioral and psychological symptoms of …
neuropsychiatric symptoms also known as behavioral and psychological symptoms of …
Depressed or demented: common CNS drug targets?
MK Sun, DL Alkon - Current Drug Targets-CNS & Neurological …, 2002 - ingentaconnect.com
A body of evidence emerging in antidepressant and antidementia research has revealed a
convergence of molecular events known to regulate neuronal plasticity in learning and …
convergence of molecular events known to regulate neuronal plasticity in learning and …
Advances in Therapeutics to Alleviate Cognitive Decline and Neuropsychiatric Symptoms of Alzheimer's Disease
J Li, A Haj Ebrahimi, AB Ali - International Journal of Molecular Sciences, 2024 - mdpi.com
Dementia exists as a 'progressive clinical syndrome of deteriorating mental function
significant enough to interfere with activities of daily living', with the most prevalent type of …
significant enough to interfere with activities of daily living', with the most prevalent type of …
Pathogenesis of depression in Alzheimer's disease
Q Zhan, F Kong, S Shao, B Zhang, S Huang - Neurochemical Research, 2024 - Springer
Depression is a prevalent occurrence among Alzheimer's disease (AD) patients, yet its
underlying mechanism remains unclear. Recent investigations have revealed that several …
underlying mechanism remains unclear. Recent investigations have revealed that several …
The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression
E Pitsillou, SM Bresnehan, EA Kagarakis… - Molecular biology …, 2020 - Springer
Major depressive disorder (MDD) is considered a serious public health issue that adversely
impacts an individual's quality of life and contributes significantly to the global burden of …
impacts an individual's quality of life and contributes significantly to the global burden of …
Novel targets for parkinsonism-depression comorbidity
Y Tizabi, B Getachew, AB Csoka, KF Manaye… - Progress in Molecular …, 2019 - Elsevier
With the aging population growing and the incidence of neurodegenerative diseases on the
rise, the researchers in the field are yet more urgently challenged to slow and/or reverse the …
rise, the researchers in the field are yet more urgently challenged to slow and/or reverse the …