[图书][B] Translational Research Methods for Major Depressive Disorder
Major depressive disorder (MDD) is a debilitating psychological disorder with a constellation
of heterogeneous symptoms characterized by altered emotional, cognitive, and behavioral …
of heterogeneous symptoms characterized by altered emotional, cognitive, and behavioral …
Mechanisms of antidepressant action: an integrated dopaminergic perspective
The molecular mechanisms that cause and maintain the major depressive disorder (MDD)
are currently unknown. Consistently, antidepressant treatments are characterized by …
are currently unknown. Consistently, antidepressant treatments are characterized by …
Major depressive disorder: hypothesis, mechanism, prevention and treatment
L Cui, S Li, S Wang, X Wu, Y Liu, W Yu… - … and Targeted Therapy, 2024 - nature.com
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …
Targeting inflammation: a potential approach for the treatment of depression
Major depressive disorder (MDD) or Depression is one of the serious neuropsychiatric
disorders affecting over 280 million people worldwide. It is 4th important cause of disability …
disorders affecting over 280 million people worldwide. It is 4th important cause of disability …
Targeting an old mechanism in a new disease—protection of glutamatergic dysfunction in depression
R Sattler, JD Rothstein - Biological psychiatry, 2007 - biologicalpsychiatryjournal.com
Depression is one of the most prevalent psychiatric disor-ders and has been estimated to
affect about 121 million people worldwide. According to the World Health Organization, it is …
affect about 121 million people worldwide. According to the World Health Organization, it is …
Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application
MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
Defeating the Dementors
P Stern - Science, 2012 - science.org
Depression is a devastating disease. It affects not only the directly afflicted but also the
people around them, their families, and their closest relations. It indiscriminately hits all …
people around them, their families, and their closest relations. It indiscriminately hits all …
The neurobiology of depression: An integrated view
J Dean, M Keshavan - Asian journal of psychiatry, 2017 - Elsevier
Abstract Major Depressive Disorder (MDD) is one of the most common and debilitating
mental disorders; however, its etiology remains unclear. This paper aims to summarize the …
mental disorders; however, its etiology remains unclear. This paper aims to summarize the …
Biomarkers for depression: recent insights, current challenges and future prospects
A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …
has not yet fully elucidated their roles in depressive illness or established what is abnormal …
Major depression, cognitive dysfunction and Alzheimer's disease: is there a link?
ASR Sierksma, DLA van den Hove… - European Journal of …, 2010 - Elsevier
Major depression (MD) is a severe mental disorder characterized by alterations in mood and
cognition, with disease severity correlating inversely with cognition scores. Neuropathology …
cognition, with disease severity correlating inversely with cognition scores. Neuropathology …