Progression‐free survival as a surrogate endpoint of overall survival in patients with metastatic renal cell carcinoma

S Halabi, B Rini, B Escudier, WM Stadler, EJ Small - Cancer, 2014 - Wiley Online Library
BACKGROUND The current study was conducted to investigate the dependence between
progression‐free survival (PFS) and overall survival (OS) in patients with metastatic renal …

[HTML][HTML] Changes in treatment reality and survival of patients with advanced clear cell renal cell carcinoma–analyses from the german clinical RCC-registry

PJ Goebell, M Staehler, L Müller, A Nusch… - Clinical Genitourinary …, 2018 - Elsevier
Introduction Because the treatment landscape for metastatic renal cell carcinoma (mRCC)
has evolved dramatically over the past decade, data on patients' treatment and outcomes in …

Treatment patterns and outcomes in patients with unresectable or metastatic renal cell carcinoma in Japan

K Harada, M Nozawa, M Uemura… - … Journal of Urology, 2019 - Wiley Online Library
Objectives To clarify treatment patterns and outcomes for patients with unresectable or
metastatic renal cell carcinoma in the molecular target therapy era in Japan. Methods A …

No improvement in renal cell carcinoma survival: a population-based study in the Netherlands

KKH Aben, TK Luth, MLG Janssen-Heijnen… - European journal of …, 2008 - Elsevier
BACKGROUND: The increased finding of kidney 'incidentalomas' and more frequent surgery
in patients with renal cell cancer (RCC) metastases may have improved survival from the …

Sequencing of agents for metastatic renal cell carcinoma: can we customize therapy?

G Sonpavde, TK Choueiri, B Escudier, V Ficarra… - European urology, 2012 - Elsevier
CONTEXT: The expanding armamentarium of agents for the therapy of advanced clear cell
renal cell carcinoma (RCC) warrants further investigation of optimal patient selection …

Trends in metastatic kidney cancer survival from the cytokine to the targeted therapy era

LC Macleod, SS Tykodi, SK Holt, JL Wright, DW Lin… - Urology, 2015 - Elsevier
Objective To evaluate population-based survival trends, compared to optimistic trial
benchmarks, in metastatic renal cell carcinoma (mRCC). Advances in medical therapy for …

[HTML][HTML] European Association of Urology guidelines on renal cell carcinoma: the 2022 update

B Ljungberg, L Albiges, Y Abu-Ghanem, J Bedke… - European urology, 2022 - Elsevier
Abstract Context The European Association of Urology (EAU) Renal Cell Carcinoma (RCC)
Guideline Panel has prepared evidence-based guidelines and recommendations for the …

Advances in renal cell carcinoma treatment

MO Grimm, I Wolff, S Zastrow… - … Advances in Urology, 2010 - journals.sagepub.com
The treatment of advanced renal cell carcinoma has been completely changed by the
development of new therapeutic modalities during the past 3 years. In this time period six …

[HTML][HTML] First-, second-, third-line therapy for mRCC: benchmarks for trial design from the IMDC

JJ Ko, TK Choueiri, BI Rini, JL Lee, N Kroeger… - British journal of …, 2014 - nature.com
Background: Limited data exist on outcomes for metastatic renal cell carcinoma (mRCC)
patients treated with multiple lines of therapy. Benchmarks for survival are required for …

Renal cell carcinoma: current status and future directions

CL Martel, PN Lara Jr - Critical reviews in oncology/hematology, 2003 - Elsevier
Although renal cell carcinoma accounts for only 3% of adult malignancies, it has been
increasing in incidence by 2–4% per year since the 1970's. Cigarette smoking, obesity and …