Lipid-based systems as promising approach for enhancing the bioavailability of poorly water-soluble drugs

K Čerpnjak, A Zvonar, M Gašperlin, F Vrečer - Acta pharmaceutica, 2013 - hrcak.srce.hr
Sažetak Low oral bioavailability as a consequence of low water solubility of drugs is a
growing challenge to the development of new pharmaceutical products. One of the most …

Lipid-based emulsion drug delivery systems—A comprehensive review

M Dhaval, P Vaghela, K Patel, K Sojitra, M Patel… - Drug delivery and …, 2022 - Springer
Lipid-based emulsion system—a subcategory of emulsion technology, has emerged as an
enticing option to improve the solubility of the steadily rising water-insoluble candidates …

Self-emulsifying drug delivery systems and their marketed products: a review

GV Betageri - Asian Journal of Pharmaceutics (AJP), 2019 - asiapharmaceutics.info
Self-emulsifying drug delivery systems (SEDDS) are one of the proven methods to increase
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …

Self-nanoemulsifying drug delivery systems (SNEDDS) and self-microemulsifying drug delivery systems (SMEDDS) as lipid nanocarriers for improving dissolution rate …

M Krstić, Đ Medarević, J Đuriš, S Ibrić - Lipid nanocarriers for drug targeting, 2018 - Elsevier
An increase in the proportion of poorly aqueous soluble drugs that exhibit problems in oral
bioavailability is one of the major problems in formulation development. Formulation of lipid …

Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs

BK Nanjwade, DJ Patel, RA Udhani, FV Manvi - Scientia pharmaceutica, 2011 - mdpi.com
Lipid-based formulations encompass a diverse group of formulations with very different
physical appearance, ranging from simple triglyceride vehicles to more sophisticated …

[PDF][PDF] Self emulsifying drug delivery system: A tool in solubility enhancement of poorly soluble drugs

K Sapra, A Sapra, SK Singh, S Kakkar - Indo Global J Pharm Sci, 2012 - academia.edu
Low aqueous solubility and thereby low oral bioavailability is a major concern for
formulation scientist as many recent drugs are lipophillic in nature and their lower solubility …

Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs

T Gershanik, S Benita - European journal of pharmaceutics and …, 2000 - Elsevier
The main purpose of this review is to provide a current and general overview of the existing
self-dispersing formulations resulting from dilution into emulsions, microemulsions and …

Oral lipid based drug delivery system (LBDDS): formulation, characterization and application: a review

A Rahman, R Harwansh, A Mirza… - Current drug …, 2011 - ingentaconnect.com
The major problem in oral drug formulations is low and erratic bioavailability, which mainly
results from poor aqueous solubility. This may lead to high inter-and intra subject variability …

Lipid‐based drug delivery systems

H Shrestha, R Bala, S Arora - Journal of pharmaceutics, 2014 - Wiley Online Library
The principle objective of formulation of lipid‐based drugs is to enhance their bioavailability.
The use of lipids in drug delivery is no more a new trend now but is still the promising …

From nanoemulsions to self-nanoemulsions, with recent advances in self-nanoemulsifying drug delivery systems (SNEDDS)

FU Rehman, KU Shah, SU Shah, IU Khan… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …