Natural killer cells and other innate lymphoid cells in cancer

L Chiossone, PY Dumas, M Vienne… - Nature Reviews …, 2018 - nature.com
Immuno-oncology is an emerging field that has revolutionized cancer treatment. Most
immunomodulatory strategies focus on enhancing T cell responses, but there has been a …

Natural killer cell engagers in cancer immunotherapy: next generation of immuno‐oncology treatments

O Demaria, L Gauthier, G Debroas… - European Journal of …, 2021 - Wiley Online Library
Immuno‐oncology is revolutionizing the treatment of cancers, by inducing the recognition
and elimination of tumor cells by the immune system. Recent advances have focused on …

Natural killer cells in cancer biology and therapy

SY Wu, T Fu, YZ Jiang, ZM Shao - Molecular cancer, 2020 - Springer
The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …

Natural killer cells: the linchpin for successful cancer immunotherapy

KA Shaver, TJ Croom-Perez, AJ Copik - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy is a highly successful and rapidly evolving treatment modality that
works by augmenting the body's own immune system. While various immune stimulation …

Targeting natural killer cells in solid tumors

G Habif, A Crinier, P André, E Vivier… - Cellular & molecular …, 2019 - nature.com
Natural killer (NK) cells are innate lymphoid cells endowed with cytolytic activity and a
capacity to secrete cytokines and chemokines. Several lines of evidence suggest that NK …

Natural killer cells and solid tumors

A Stojanovic, A Cerwenka - Journal of innate immunity, 2011 - karger.com
Natural killer (NK) cells play an important role in the innate immune response against
cancer, in particular in the elimination of tumor metastases and small tumors. NK cell …

Therapeutic potential and challenges of natural killer cells in treatment of solid tumors

A Gras Navarro, AT Björklund, M Chekenya - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are innate lymphoid cells that hold tremendous potential for effective
immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring …

NK cell therapy: a rising star in cancer treatment

N Du, F Guo, Y Wang, J Cui - Cancers, 2021 - mdpi.com
Simple Summary A cancer treatment approach known as immunotherapy has become
popular in the medical field. In this case, immune cells are boosted for effective response …

[HTML][HTML] Human natural killer cells and other innate lymphoid cells in cancer: friends or foes?

P Vacca, E Munari, N Tumino, F Moretta, G Pietra… - Immunology …, 2018 - Elsevier
Innate lymphoid cells (ILC) including NK cells (cytotoxic) and the recently identified “helper”
ILC1, ILC2 and ILC3, play an important role in innate defenses against pathogens. Notably …

Targeting natural killer cells and natural killer T cells in cancer

E Vivier, S Ugolini, D Blaise, C Chabannon… - Nature Reviews …, 2012 - nature.com
Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share
some phenotypical and functional similarities. Both cell types can rapidly respond to the …