Understanding cardiovascular disease: a journey through the genome (and what we found there)
E Lara-Pezzi, A Dopazo… - Disease models & …, 2012 - journals.biologists.com
Cardiovascular disease (CVD) is a major cause of mortality and hospitalization worldwide.
Several risk factors have been identified that are strongly associated with the development …
Several risk factors have been identified that are strongly associated with the development …
Machine learning–based risk assessment for cancer therapy–related cardiac dysfunction in 4300 longitudinal oncology patients
Background The growing awareness of cardiovascular toxicity from cancer therapies has led
to the emerging field of cardio‐oncology, which centers on preventing, detecting, and …
to the emerging field of cardio‐oncology, which centers on preventing, detecting, and …
[HTML][HTML] Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease
W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are disorders associated with the heart and circulatory
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …
Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice
DH Roukos - Biomarkers in medicine, 2010 - Taylor & Francis
In their day-to-day clinical practice, physicians are facing the adverse effects and limited
effectiveness of currently used drugs in the treatment of major diseases. Biomarkers …
effectiveness of currently used drugs in the treatment of major diseases. Biomarkers …
Identifying novel biomarkers for cardiovascular disease risk prediction
The primary prevention of cardiovascular disease relies on the ability to identify at‐risk
individuals long before the development of overt events. In the past decade, research into …
individuals long before the development of overt events. In the past decade, research into …
Protein biomarkers of new-onset cardiovascular disease: prospective study from the systems approach to biomarker research in cardiovascular disease initiative
X Yin, S Subramanian, SJ Hwang… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Incorporation of novel plasma protein biomarkers may improve current models
for prediction of atherosclerotic cardiovascular disease (ASCVD) risk. Approach and Results …
for prediction of atherosclerotic cardiovascular disease (ASCVD) risk. Approach and Results …
Risk of cardiometabolic risk factors in women with and without a history of breast cancer: the pathways heart study
ML Kwan, RK Cheng, C Iribarren… - Journal of clinical …, 2022 - ascopubs.org
PURPOSE The incidence of cardiometabolic risk factors in breast cancer (BC) survivors has
not been well described. Thus, we compared risk of hypertension, diabetes, and …
not been well described. Thus, we compared risk of hypertension, diabetes, and …
Molecular pathways for cancer angioprevention
By analogy to the success of cardiovascular medicine in reducing mortality through
preventive measures, cancer chemoprevention has the potential to significantly reduce …
preventive measures, cancer chemoprevention has the potential to significantly reduce …
[HTML][HTML] The role of CYP450 drug metabolism in precision cardio-oncology
OA Fatunde, SA Brown - International journal of molecular sciences, 2020 - mdpi.com
As many novel cancer therapies continue to emerge, the field of Cardio-Oncology (or onco-
cardiology) has become crucial to prevent, monitor and treat cancer therapy-related …
cardiology) has become crucial to prevent, monitor and treat cancer therapy-related …
[HTML][HTML] Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets
Abstract The European Union multi-disciplinary Personalised RNA interference to Enhance
the Delivery of Individualised Cytotoxic and Targeted therapeutics (PREDICT) consortium …
the Delivery of Individualised Cytotoxic and Targeted therapeutics (PREDICT) consortium …