Network pharmacology and molecular docking-based identification of drug candidates and key targets of Allium sativum for colorectal cancer treatment
OF Olukunle, V Omoboyede… - Journal of Biomolecular …, 2024 - Taylor & Francis
Colorectal cancer (CRC) is a type of cancer with high morbidity and mortality in several
developing and developed countries of the world. Its mortality and morbidity are predicted to …
developing and developed countries of the world. Its mortality and morbidity are predicted to …
Natural products for treatment of Plasmodium falciparum malaria: An integrated computational approach
Malaria is a life-threatening infectious disease with an estimated 229 million cases in the
year 2019 worldwide. Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate …
year 2019 worldwide. Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate …
[PDF][PDF] Phytochemistry, Laxative, Prokinetic and Spasmolytic Verification of Withania somnifera (L.) Dunal Using In-Vitro, In-Vivo and In-Silico Approaches
Background: Withania somnifera (L.) Dunal is traditionally used as laxative, diuretic and
sedative remedy. The current study was aimed to perform phytochemical analysis …
sedative remedy. The current study was aimed to perform phytochemical analysis …
Antimalarial activities of a therapeutic combination of Azadirachta indica, Mangifera indica and Morinda lucida leaves: a molecular view of its activity on Plasmodium …
Background The search for new antimalarial drugs remains elusive prompting research into
antimalarial combinations from medicinal plants due to their cheapness, efficacy and …
antimalarial combinations from medicinal plants due to their cheapness, efficacy and …
Assessment of bio-activities of the crude extract and components of Withania somnifera leaves by bioinformatics
Traditional herbal medicines are now increasingly being appreciated with Western models
of integrative health sciences and evidence-based approach both in the basic research and …
of integrative health sciences and evidence-based approach both in the basic research and …
In silico analysis of soybean phytocompounds against Plasmodium falciparum
Introduction Natural products have been indispensable since immemorial and still act as a
supportive healer. Parasitic diseases are a significant hurdle for humans and are …
supportive healer. Parasitic diseases are a significant hurdle for humans and are …
Bisbenzylisoquinolines from Cissampelos pareira L. as antimalarial agents: Molecular docking, pharmacokinetics analysis, and molecular dynamic simulation studies
PS Suresh, V Kesarwani, S Kumari, R Shankar… - … Biology and Chemistry, 2023 - Elsevier
Malaria is a major global health issue due to the emergence of resistance to most of the
available antimalarial drugs. There is an urgent need to discover new antimalarials to tackle …
available antimalarial drugs. There is an urgent need to discover new antimalarials to tackle …
Diet-induced animal model anti-obesity, phytochemical profiling, and in silico analysis of culinary plant gokhru (Pedalium murex L.) mucilage
P Jeyakumar, AR Jasmin Suriya… - Journal of …, 2023 - Taylor & Francis
Plant-based diets (PBDs) are renowned for managing and developing bioactive chemical
inhibitors to combat obesity, a well-known global public health concern. There are currently …
inhibitors to combat obesity, a well-known global public health concern. There are currently …
Elucidating the interaction and stability of withanone and withaferin‐a with human serum albumin, lysozyme and hemoglobin using computational biophysical …
S Rajkhowa, U Pathak, H Patgiri - ChemistrySelect, 2022 - Wiley Online Library
Withania somnifera consists of various bioactive compounds, of which withanone (WT− N)
and withaferin‐A (WT− A) are known to have many therapeutic properties. To understand …
and withaferin‐A (WT− A) are known to have many therapeutic properties. To understand …
Identification and molecular docking studies of bioactive principles from Alphonsea madraspatana Bedd. against uropathogens
Aims: The present study aims to determine the antimicrobial efficacy of Alphonsea
madraspatana leaves extract against selected uropathogens. Background: The plant …
madraspatana leaves extract against selected uropathogens. Background: The plant …