Pharmacological treatment of depression in Alzheimer's disease: a challenging task

T Cassano, S Calcagnini, A Carbone… - Frontiers in …, 2019 - frontiersin.org
Besides the memory impairment, Alzheimer's disease (AD) is often complicated by
neuropsychiatric symptoms also known as behavioral and psychological symptoms of …

Converged avenues: depression and Alzheimer's disease–shared pathophysiology and novel therapeutics

S Bajaj, R Mahesh - Molecular Biology Reports, 2024 - Springer
Depression, a highly prevalent disorder affecting over 280 million people worldwide, is
comorbid with many neurological disorders, particularly Alzheimer's disease (AD) …

Depression in Alzheimer's disease: epidemiology, mechanisms, and management

S Chi, JT Yu, MS Tan, L Tan - Journal of Alzheimer's disease, 2014 - content.iospress.com
Depression occurs with a high prevalence of up to 50% in patients with Alzheimer's disease
(AD) and increases the caregivers' burden. Depression symptoms can precede clinical …

What is the association between depression and Alzheimer's disease?

N Tsuno, A Homma - Expert review of neurotherapeutics, 2009 - Taylor & Francis
Depression and dementia, in particular Alzheimer's disease (AD), are critically important
issues in the mental health of old age. Both conditions apparently reduce quality of life and …

Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease

M Aboukhatwa, L Dosanjh, Y Luo - Molecular neurodegeneration, 2010 - Springer
There is a high prevalence rate (30-50%) of Alzheimer's disease (AD) and depression
comorbidity. Depression can be a risk factor for the development of AD or it can be …

Depression and Alzheimer's disease: neurobiological links and common pharmacological targets

F Caraci, A Copani, F Nicoletti, F Drago - European journal of …, 2010 - Elsevier
Depression is one of the most prevalent and life-threatening forms of mental illnesses,
whereas Alzheimer's disease is a neurodegenerative disorder that affects more than 37 …

Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment

YY Huang, YH Gan, L Yang, W Cheng, JT Yu - Biological Psychiatry, 2023 - Elsevier
Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between two disease entities has received extensive acknowledgment, yet …

The putative neurodegenerative links between depression and Alzheimer's disease

S Wuwongse, RCC Chang, ACK Law - Progress in Neurobiology, 2010 - Elsevier
Alzheimer's disease (AD) is the leading neurodegenerative cause of dementia in the elderly.
Thus far, there is no curative treatment for this devastating condition, thereby creating …

Neuropathology of depression in Alzheimer's disease: current knowledge and the potential for new treatments

AA Khundakar, AJ Thomas - Journal of Alzheimer's Disease, 2015 - content.iospress.com
Depression is among the most common behavioral and psychological symptoms of
dementia, and leads to more rapid decline and higher mortality. Treatment for depression in …

Major depression, cognitive dysfunction and Alzheimer's disease: is there a link?

ASR Sierksma, DLA van den Hove… - European Journal of …, 2010 - Elsevier
Major depression (MD) is a severe mental disorder characterized by alterations in mood and
cognition, with disease severity correlating inversely with cognition scores. Neuropathology …