100 YEARS OF INSULIN: 100 years of insulin: progress, current perspectives and future
challenges in: Journal of Endocrinology Volume 252 Issue 3 (2022) Jump to Content Jump to …

Abstract We thank Dr Davidson [1] for his interest in our paper,[2] which observed the non-
linear relationship between insulin doses resulting in smaller reductions in fasting plasma …

With the exception of insulin, all diabetes medications have limited glucose-lowering
capacity. Therefore, as type 2 diabetes progresses, insulin is often needed to achieve near …

Insulin is the key anabolic hormone of metabolism, with clear effects on glycaemia. Near-
complete insulin deficiency occurs in type 1 diabetes (T1D), the predominant form affecting …

Since the last guidelines were published in 2009 (1) the changes have been modest with
respect to insulin treatment, but the different modes have been refined especially when it …

A prime target of insulin action in patients with maturity onset diabetes is suppression of
hepatic glucose production in both the fasting and postprandial states. In patients who fail to …

This document was downloaded for personal use only. Unauthorized distribution is strictly
prohibited. givers and patients. Basically, the term ªintensiveº insulin therapy describes a …

In 1998, the American Diabetes Associ-ation (ADA) announced an ambitious 5-year plan for
funding research, namely that by Fiscal Year 2003, one of three Total Public Support dollars …

Insulin has been available for the treatment of diabetes for almost a century, and the variety
of insulin choices today represents many years of discovery and innovation. Insulin has …