Clonal haematopoiesis (CH) is a common, age-related expansion of blood cells with
somatic mutations that is associated with an increased risk of haematological malignancies …

Clonal hematopoiesis (CH), characterized by blood cells predominantly originating from a
single mutated hematopoietic stem cell, is linked to diverse aging-related diseases …

Clonal hematopoiesis (CH) represents the clonal expansion of hematopoietic stem cells and
their progeny driven by somatic mutations. Accurate risk assessment of CH is critical for …

Loss of the Y chromosome (LOY) is one of the most common somatic genomic alterations in
hematopoietic cells in men. However, due to the high prevalence of LOY as the sole …

Mosaic loss of the X chromosome (mLOX) is the most commonly occurring clonal somatic
alteration detected in the leukocytes of women, yet little is known about its genetic …

Mosaic loss of chromosome Y (mLOY) in blood cells is one of the most frequent
chromosome alterations in adult males. It is strongly associated with clonal hematopoiesis …

Background: Risk factors including smoking, alcohol intake, physical activity (PA), and sleep
patterns have been associated with cancer risk. Clonal hematopoiesis (CH), including …

Background Clonal hematopoiesis of indeterminate potential (CHIP), the age-related
expansion of mutant hematopoietic stem cells, confers risk for multiple diseases of aging …

Characterized by the accumulation of somatic mutations in blood cell lineages, clonal
hematopoiesis of indeterminate potential (CHIP) is frequent in aging and involves the …

Purpose Most chromosome abnormality patients require long-term clinical care. Awareness
of mosaicism and comorbidities can potentially guide such health care. Here we present a …