Cancerous diseases present a formidable health problem worldwide. While the
chemotherapy of cancer, in conjunction with other treatment modalities, has reached a …

Use of polymeric drug delivery systems is rapidly becoming an established approach for
improvement of cancer chemotherapy. Zoladex (R), a poly lactide-co-glycolide …

Cancerous diseases, together with cardiac afflictions, account for the predominant causes of
death among the adult population of the Western world. The classical platinum drugs, with …

Despite much progress in the chemotherapy of cancerous diseases, antitumor drugs in
current clinical use suffer from major pharmacological deficiencies. The platinum drug …

Cancer is the second worldwide cause of death following cardiovascular diseases.
Chemotherapy is the gold standard strategy for effective treatment of cancer. However, the …

Interdisciplinary research at the interface of polymer chemistry and the biomedical sciences
has produced the first polymer-based nanomedicines for the diagnosis and treatment of …

The discovery of new molecular targets and the subsequent development of novel
anticancer agents are opening new possibilities for drug combination therapy as anticancer …

Although clinical trials using macromolecular conjugates of cytotoxic drugs in a treatment of
malignant disease are fragmentary at best, a number of carrier systems that have been …

Drug delivery systems for cancer therapeutics have revolutionized medicine. Delivery
systems have improved the efficacy and reduced the toxicity of current therapies and …

Polymer conjugates may possess anticancer activity through a variety of mechanisms. The
macro-molecules themselves may have anticancer activities, or, more typically, inert …