Abstract Formulation with sustained release profiles is highly desired for the treatment of
bipolar disorder (BD) to improve patient compliance by avoiding frequent dosing and …

This study aims to develop and characterize a solid lipid nanoparticle (SLN) formulation for
the anti-psychotics drug clozapine to improve drug delivery efficiency. Using a modified high …

Nanosuspension is a term that can be used to describe a colloidal dispersion of nanosized
droplets of the drug in an aqueous medium with a size below 1μm. Drug nanoparticles are …

Context: Nasal route of drug administration is preferred more and more for the targeted
delivery to the brain in current drug development scenario due to its ease of use, reliability …

The objective of the work was to formulate and evaluate solid lipid nanoparticles loaded with
clozapine for use in the treatment of schizophrenia. Solid Lipid Nanoparticles was prepared …

The treatment of schizophrenia has advanced because the therapeutic efficacy, tolerability,
and safety profiles of atypical antipsychotics. Amisulpride is an atypical antipsychotic drug …

Systemic drug delivery in schizophrenia is a major challenge due to presence of obstacles
like, blood-brain barrier and P-glycoprotein, which prohibit entry of drugs into the brain …

Background Quetiapine (QTP) is a first-line antipsychotic drug, but its therapeutic
druggability and patient adherence were limited due to high oral dose strength, low …

The objective of this study was to investigate the effect of the different physiological
parameters of the gastrointestinal (GI) fluid (pH, buffer capacity, and ionic strength) on the in …

The present paper discusses the design, characterization and in vivo evaluation of glyceryl
monostearate nanoparticles of Olanzapine, an atypical antipsychotic drug for acute …