Duration of antibiotic therapy for Staphylococcus aureus bacteraemia: the long and the short of it

EM Eichenberger, VG Fowler… - Clinical …, 2020 - clinicalmicrobiologyandinfection …
The optimal duration of antibiotic therapy for Staphylococcus aureus bacteraemia (SAB)
remains controversial despite over a half century of debate. In the 1940s, limited supplies of …

Long versus short course anti-MICROBIAL therapy of uncomplicated STAPHYLOCOCCUS aureus bacteraemia: a systematic review

M Schnizer, P Schellong, N Rose… - Clinical Microbiology …, 2024 - Elsevier
Background Current guidelines recommend at least two weeks duration of antibiotic therapy
(DOT) for patients with uncomplicated Staphylococcus aureus bacteraemia (SAB) but the …

[HTML][HTML] Association between treatment duration and mortality or relapse in adult patients with Staphylococcus aureus bacteraemia: a retrospective cohort study

M Abbas, A Rossel, MEA De Kraker, E Von Dach… - Clinical Microbiology …, 2020 - Elsevier
Objectives The aim was to evaluate the effect of duration of therapy (DOT) on mortality and
relapse for patients with Staphylococcus aureus bacteraemia (SAB). Methods We performed …

Treatment duration for uncomplicated Staphylococcus aureus bacteremia to prevent relapse: analysis of a prospective observational cohort study

YP Chong, SM Moon, KM Bang, HJ Park… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Practice guidelines recommend at least 14 days of antibiotic therapy for uncomplicated
Staphylococcus aureus bacteremia (SAB). However, these recommendations have not been …

[HTML][HTML] Impact of antimicrobial treatment duration on outcome of Staphylococcus aureus bacteraemia: a cohort study

CJ Kim, KH Song, KH Park, M Kim, PG Choe… - Clinical Microbiology …, 2019 - Elsevier
Objectives To assess the outcome of Staphylococcus aureus bacteraemia (SAB) according
to factors associated with necessity for longer treatment in conjunction with the duration of …

Shortening the Duration of Therapy for Staphylococcus aureus Bacteremia: Opening the Overton Window

SYC Tong, G Walls - Clinical Infectious Diseases, 2021 - academic.oup.com
Recent clinical trials have demonstrated that shorter durations of antibiotic treatment are as
effective as longer durations for infectious diseases syndromes including pneumonia [1] and …

[HTML][HTML] Factors associated with 12 week case-fatality in Staphylococcus aureus bacteraemia: a prospective cohort study

P Braquet, F Alla, C Cornu, F Goehringer… - Clinical Microbiology …, 2016 - Elsevier
Staphylococcus aureus bacteraemia (SAB) is a frequent and deadly disease. Given the lack
of a randomized trial, optimal first-line antibiotic treatment is still debated. Our aim was to …

Short-term versus usual-term antibiotic treatment for uncomplicated Staphylococcus aureus bacteremia: a systematic review and meta-analysis

S Grillo Perez, C Diaz-Brochero… - Therapeutic …, 2024 - journals.sagepub.com
Introduction: Uncomplicated Staphylococcus aureus bacteremia remains a leading cause of
morbidity and mortality in hospitalized patients. Current guidelines recommend a minimum …

[HTML][HTML] Impact of shorter (< 14 days) antibiotic treatment duration in adults with uncomplicated Staphylococcus aureus bacteremia: a systematic review and meta …

V Zanichelli, F Olearo, AM Aiken - Clinical Infection in Practice, 2024 - Elsevier
Objectives Staphylococcus aureus is an important cause of bloodstream infections. We
aimed to summarize associations between different antibiotic durations (< 14 days versus …

Defining the Breakpoint Duration of Staphylococcus aureus Bacteremia Predictive of Poor Outcomes

E Minejima, N Mai, N Bui, M Mert… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Persistent Staphylococcus aureus bacteremia (SAB) is defined based
on varying duration in literature. The primary objective was to determine the risk of poor …