In this issue of Trends in Cardiovascular Medicine, Drs. Bradley and Rumsfeld1 provide a
clear, contemporary review of the phenomenology, assessment, and treatment of …

Depression and heart disease have an intricate association and perhaps a causal
relationship. We review the current status of depression and heart disease and provide an …

In 1628, William Harvey defined the circulatory system as we know it and proposed a link
between the mind and the heart. This potential association received little attention for 300 …

Major depressive disorder is a risk factor for the development of incident coronary heart
disease events in healthy patients and for adverse cardiovascular outcomes in patients with …

Importance of the field: Coronary heart disease (CHD) and depression are two leading
causes of death and disability in the United States and worldwide. Depression is especially …

The relationship between cardiovascular disease and depression poses intriguing research
questions, particularly for co-morbid treatment. Preliminary studies have indicated that …

Background and Objectives Depression in patients with Cardiovascular Disease (CVD) is
extremely common, with a prevalence of 17–47%, and is associated with increased risk of …

Context Several practice guidelines recommend that depression be evaluated and treated in
patients with cardiovascular disease, but the potential benefits of this are unclear. Objective …

Depression occurs in 10% to 20% of post–myocardial infarction (MI) patients and 15% to
30% of heart failure (HF) patients. Depression has been associated with an increased risk of …

There is extensive evidence that depression at the time of the initial diagnosis of coronary
artery disease (CAD), and again following an acute cardiac event, increases the risk for …