Polyamines contribute to several physiological and pathological processes, including
cardiac hypertrophy in experimental animals. This involves an increase in ornithine …

The activity of rat heart ornithine decarboxylase (ODC), the enzyme involved in the initial
step of polyamine biosynthesis, was markedly stimulated after isoproterenol treatment …

Polyamines are believed to have an essential role in cellular growth and differentiation.
Activation of ornithine decarboxylase, the initial rate-limiting enzyme in polyamine …

Polyamines (putrescine, spermidine and spermine) are considered to act as intracellular
second messengers by increasing Ca++ influx and mobilizing intracellular calcium. On the …

Cardiac polyamines are thought to protect the myocardium against harmful stimuli and to be
regulated by sympathetic nerve activation. In the present study, polyamines concentrations …

Ornithine decarboxylase activity in rat heart was increased significantly by the injection of l-
norepinephrine or nisoxetine, an inhibitor of norepinephrine uptake. The enzyme was also …

Ornithine decarboxylase (ODC), the rate-limiting enzyme in the biosynthesis of polyamines,
displays high activity early in postnatal development of the heart, followed by a gradual …

The aliphatic amines, spermine and spermidine, and amino-oxidase activity were evaluated
in hypertrophic rabbit heart obtained following aortic arch constriction. The polyamines were …

FELDMAN, MARVIN J., AND DIANE H. RUSSELL. Polyamine biowesis in left ventricle of the
rat hart after aortic constriction. Am. J. f'lqGol. 222 (5): 11994203. 1972.-The enzymes …

Objective: The aims were to investigate the requirement for and regulation of cellular
polyamines during vascular endothelial cell proliferation. Methods: Proliferation of cultured …