Proliferation of smooth muscle cells (SMC), enhancement of polyamine biosynthesis and
increase in polyamine level in response to deendothelialization in the rat aorta were …

Inhibition of cardiac ornithine decarboxylase (ODC) by α-difluoromethylornithine (DFMO) did
not prevent normal cardiac growth in mature rats but attenuated isoproterenol-induced …

Myocardial ornithine decarboxylase activity has been measured in the right and left
ventricles of rats subjected to hypobaric conditions. Control normobaric groups included …

Objective: The aim was to investigate the involvement of polyamines in the development of
cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension. Methods …

Endogenous polyamines play a key role in mediating cellular growth and differentiation.
Hypertension is associated with structural modifications of the circulatory system, a process …

N the presence of hypertension, the heart becomes enlarged and myocardial protein
synthesis is enhanced. 1= 2" Anti-hypertensive treatment should not only lower blood …

In the rat heart, there is a remarkable remodeling due to catecholamines. As to the functional
effects, norepinephrine (NE) induced a marked positive chronotropic effect and an elevation …

Polyamines (putrescine, spermidine, and spermine) are present in all higher eukaryotic cells
and are essential for cell growth, differentiation and apoptosis. Sharing common precursor …

Ornithine decarboxylase activity was higher in the left ventricle than in the right ventricle of
the rat. Swimming exercise for 2 hours caused an increase in left ventricular but not right …

Among the mechanisms that have been proposed to be involved in the stimulation of protein
synthesis associated with the development of cardiac hypertrophy [I, 6, 7, 8, 9, 11, 12, 14 …