The effect of catabolic states induced by hyperthyroidism, hypercorticolism, and fasting on muscle ornithine decarboxylase activity

EW Chideckel, EB Belur - Endocrinology, 1980 - academic.oup.com
Ornithine decarboxylase is a rate-limiting step in the formation of the polyamines
(putrescine, spermidine, and spermine). Ornithine decarboxylase activity (ODC) is increased …

Heart ornithine decarboxylase from control and isoproterenol-treated rats: kinetic properties, multiple forms and subcellular distribution.

F Flamigni, C Guarnieri, CM Caldarera - General Pharmacology, 1986 - europepmc.org
Heart ornithine decarboxylase (ODC) from isoproterenol treated rats was compared to heart
ODC from control rats. Isoproterenol administration did not significantly change Km for …

The role of polyamines in β-adrenergic stimulation of calcium influx and membrane transport in rat heart

CC Fan, H Koenig - Journal of molecular and cellular cardiology, 1988 - Elsevier
The β-adrenergic agonist 1-isoproterenol induced an early (< 1 min) stimulation of
endocytosis, amino acid transport and hexose transport, monitored by the temperature …

Effect of indapamide on cyclic adenosine 3', 5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac …

SW Rabkin - Journal of cardiovascular pharmacology, 1993 - journals.lww.com
The objective of this study was to examine the effect of indapamide on cAMP generation in
cardiomyocytes. Viable ventricular myocytes were isolated from adult rat hearts which …

Adrenergic activity as a modulating factor in the genesis of myocardial hypertrophy in the rat

A Genovese, M Chiariello, M Bozzaotre, S Latte… - … and molecular pathology, 1984 - Elsevier
Abstract Sprague Dawley male rats (200–220 g) were subjected to a long-term treatment
with low doses of catecholamines in an attempt to assess the effect of the adrenergic …

Catecholamine-induced cardiac hypertrophy in a denervated, hemodynamically non-stressed heart transplant

DF Larson, JG Copeland, DH Russell - Life sciences, 1985 - Elsevier
Studies of stress-induced cardiac hypertrophy suggest that myocardial mass is regulated by
the circulating level of epinephrine. The trophic effect is mediated by cardiac beta …

Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia

B Tantini, E Fiumana, S Cetrullo, C Pignatti… - Journal of molecular and …, 2006 - Elsevier
Apoptotic cell death of cardiomyocytes is involved in several cardiovascular diseases
including ischemia, hypertrophy, and heart failure. The polyamines putrescine, spermidine …

Monoamine oxidase and semicarbazide-sensitive amine oxidase activities in isolated cardiomyocytes of spontaneously hypertensive rats

R Pino, P Failli, L Mazzetti, F Buffoni - Biochemical and Molecular Medicine, 1997 - Elsevier
In the isolated cardiomyocytes of spontaneously hypertensive rats (SHR, 3 months old) MAO
A and B activities were significantly increased compared to the myocytes in the hearts of age …

The in-vitro and in-vivo effects of polyamines on cardiac protein biosynthesis

K GIBSON, P HARRIS - Cardiovascular Research, 1974 - academic.oup.com
AUTHORS'SYNOPSIS In cell-free systems putrescine, spermine, and spermidine at
concentrations of 15 to 100 μg had no significant effect at 11 mM Mg2+ on rat myocardial …

Inhibition of polyamine formation antagonizes vascular smooth muscle cell proliferation and preserves the contractile phenotype

M Grossi, L Persson, K Swärd… - Basic & clinical …, 2014 - Wiley Online Library
The polyamines putrescine, spermidine and spermine play essential roles in cell
proliferation and migration, two processes involved in the development of vascular disease …