Radiotherapy (RT) primarily aims to locally destroy the tumor via the induction of DNA
damage in the tumor cells. However, the so-called abscopal, namely systemic and immune …

Dendritic cells are key orchestrators of the immune system. There is considerable interest in
their use for treating cancer. Whether they initiate an effective cytotoxic response against …

Purpose: In the proper context, radiotherapy can promote antitumor immunity. It is unknown
if elective nodal irradiation (ENI), a strategy that irradiates tumor-associated draining lymph …

A clear contribution of the immune system to eradication of tumors has been supported by
recent developments in the field of immunotherapy. Durable clinical responses obtained …

Since the beginning of the 20th century, scientists have tried to stimulate the antitumour
activities of the immune system to fight against cancer. However, the scientific effort devoted …

The capacity of lymph nodes to eradicate cancer is a controversial issue. The purpose of this
study was to determine the interplay between tumor growth and host resistance at early …

Simple Summary Tertiary lymphoid structures (TLS) are anatomic entities that are similar to,
but distinct from, secondary lymphoid structures (eg, lymph nodes) that allow for a host's own …

ABSTRACT Introduction: Tumor-infiltrating lymphocytes (TILs) are frequently observed in
several tumors, reflecting the dynamic process of '“cancer immunoediting”'. Prognostic and …

Ionizing radiation therapy (RT) is an important local modality for the treatment of cancer. The
current rationale for its use is based largely on the ability of RT to kill the cancer cells by a …

Radiotherapy (RT) is one of the main components in the treatment of cancer. The better
understanding of the immune mechanisms associated with tumor establishment and how RT …