The lymphatic system was first described centuries ago. The recent discovery of various
molecular markers has allowed for more in-depth research of the lymphatic system and its …

Radiotherapy applies ionizing irradiation to selected areas of the body with the scope of
destroying cancer cells, either as part of curative therapies to remove a primary malignant …

We examined whether radiotherapy (RT) could enhance the efficacy of dendritic cell (DC)-
based immunotherapy of cancer. Mice bearing sc D5 melanoma or MCA 205 sarcoma …

Ectopic lymphoid tissue, also known as tertiary lymphoid organs (TLO) develop adaptively
within sites of chronic tissue inflammation, thereby allowing the host to efficiently crossprime …

Radiotherapy is part of the standard of care treatment for a great majority of cancer patients.
As a result of radiation, both tumor cells and the environment around them are affected …

Purpose: The aim of this review is to highlight key evidence supporting the effect of radiation
therapy on tumor immunity. Conclusions: Recent findings in both the preclinical and clinical …

Traditional therapies for cancer include surgery, chemotherapy, and radiation.
Chemotherapy has widespread systemic cytotoxic effects against tumor cells but also affects …

Therapeutic cancer vaccines show promise in preclinical studies, yet their clinical efficacy is
limited. Increased recruitment of immune cells into tumors and suppression of the immune …

Successful clinical methods for tumor elimination include a combination of surgical
resection, radiotherapy, and chemotherapy. Radiotherapy is one of the crucial components …

Traditional factors of DNA damage and tumor cell kill, described by the “4 R's” of
radiobiology (Reassortment, Reoxygenation, Repair, and Repopulation) fall short in …