Structure and activity of pentacyclic triterpenes codrugs. A review

J Żwawiak, A Pawełczyk, D Olender… - Mini Reviews in …, 2021 - ingentaconnect.com
Triterpenes are a wide and important group of compounds that have several promising
pharmacological properties, such as hepatoprotective, anti-inflammatory, anti-HIV …

Prodrugs of triterpenoids and their derivatives

M Zhou, RH Zhang, M Wang, GB Xu, SG Liao - European Journal of …, 2017 - Elsevier
Triterpenoids are structurally diverse organic compounds that exist widely as natural
products. Triterpenoids and their derivatives possess a wide range of biological effects …

[PDF][PDF] Triterpenoids: synthesis, uses in cancer treatment and other biological activities

LA Rascon-Valenzuela, H Torres Moreno… - Advances in Medicine …, 2017 - researchgate.net
Triterpenoids are widely distributed in both edible plants and ethnomedicinal plants; they
can also be found in any animals and marine organisms. These compounds are structurally …

Click reactions in chemistry of triterpenes-advances towards development of potential therapeutics

J Pokorny, L Borkova, M Urban - Current Medicinal Chemistry, 2018 - ingentaconnect.com
Triterpenoids are natural compounds with a large variety of biological activities such as
anticancer, antiviral, antibacterial, antifungal, antiparazitic, antiinflammatory and others …

Semisynthetic derivatives of pentacyclic triterpenes bearing heterocyclic moieties with therapeutic potential

G Nistor, C Trandafirescu, A Prodea, A Milan, A Cristea… - Molecules, 2022 - mdpi.com
Medicinal plants have been used by humans since ancient times for the treatment of various
diseases and currently represent the main source of a variety of phytocompounds, such as …

Known triterpenes and their derivatives as scaffolds for the development of new therapeutic agents for cancer

G Peron, G Marzaro… - Current medicinal …, 2018 - ingentaconnect.com
Background: Plants produce several bioactive secondary metabolites whose are used as
therapeutic agents to treat several diseases, among whom cancer. Triterpenes are …

A link between chemical structure and biological activity in triterpenoids

L Zang, H Xu, C Huang, C Wang… - Recent Patents on …, 2022 - ingentaconnect.com
Background: Plants that are rich in triterpenoid compounds possess various biological
activities and are reported in many scientific works. Triterpenoids, because of their broad …

Advances in chemistry and pharmacology of triterpenoid synthetic dimers

B Bednarczyk-Cwynar, A Günther - Current Medicinal …, 2017 - ingentaconnect.com
This review focuses on advances in chemistry and pharmacology of synthetic triterpenoid
dimers, obtained from natural compounds. Synthetic triterpenoid dimers are divided into …

Pentacyclic triterpenoids with nitrogen-and sulfur-containing heterocycles: synthesis and medicinal significance

M Kvasnica, M Urban, NJ Dickinson, J Sarek - Natural product reports, 2015 - pubs.rsc.org
Covering: 1962 to 2014 Triterpenoids are natural compounds with a variety of biological
activities and are usually produced by plants as secondary metabolites. In recent decades …

Nanoformulations for delivery of pentacyclic triterpenoids in anticancer therapies

A Kaps, P Gwiazdoń, E Chodurek - Molecules, 2021 - mdpi.com
The search for safe and effective anticancer therapies is one of the major challenges of the
21st century. The ineffective treatment of cancers, classified as civilization diseases …