Current strategies for tapering psychiatric drugs: differing recommendations, impractical doses, and other barriers

JK Eserian, VP Blanco, LP Mercuri… - Psychiatry …, 2023 - Elsevier
While effective ways to prevent withdrawal symptoms from psychiatric drugs remain unclear,
a highly accepted clinical approach for treatment discontinuation is to gradually reduce …

Potential Adverse Effects of Discontinuing Psychotropic Drugs: Part 4: Benzodiazepine, Glutamate, Opioid, and Stimulant Drugs

RH Howland - Journal of psychosocial nursing and mental …, 2010 - journals.healio.com
For nurses in clinical practice, understanding the pharmacology of drugs their patients take
is relevant to understanding their therapeutic uses, side effect profiles, and adverse …

[HTML][HTML] Gradually tapering off antipsychotics: lessons for practice from case studies and neurobiological principles

MA Horowitz, J Moncrieff - Current Opinion in Psychiatry, 2024 - journals.lww.com
Slower tapering of antipsychotics may provide time for adaptations made to the presence of
the medications to resolve, thus reducing the disruption to homeostatic equilibrium caused …

[HTML][HTML] Discontinuation of psychotropic medication: a synthesis of evidence across medication classes

CH Vinkers, RW Kupka, BW Penninx, HG Ruhé… - Molecular …, 2024 - nature.com
Pharmacotherapy is an effective treatment modality across psychiatric disorders.
Nevertheless, many patients discontinue their medication at some point. Evidence-based …

Outcome of antidepressant drug discontinuation with taperingstrips after 1–5 years

PC Groot, J van Os - Therapeutic advances in …, 2020 - journals.sagepub.com
Background: Stopping antidepressants is often difficult due to withdrawal. Taperingstrips
were developed to facilitate antidepressant discontinuation according to the recently …

Discontinuing psychotropic drugs from participants in randomized controlled trials: a systematic review

D Cohen, A Recalt - Psychotherapy and psychosomatics, 2019 - karger.com
Abstract Background and Objective: Methods and justifications for discontinuing
psychotropic drugs in randomized controlled trials (RCTs), and RCTs' acknowledgement of …

How user knowledge of psychotropic drug withdrawal resulted in the development of person-specific tapering medication

PC Groot, J van Os - Therapeutic advances in …, 2020 - journals.sagepub.com
Coming off psychotropic drugs can cause physical as well as mental withdrawal, resulting in
failed withdrawal attempts and unnecessary long-term drug use. The first reports about …

Polypharmacy or medication washout: an old tool revisited

DA Hoffman, M Schiller, JM Greenblatt… - Neuropsychiatric …, 2011 - Taylor & Francis
There has been a rapid increase in the use of polypharmacy in psychiatry possibly due to
the introduction of newer drugs, greater availability of these newer drugs, excessive …

[图书][B] Your drug may be your problem: How and why to stop taking psychiatric medications

P Breggin, D Cohen - 2007 - books.google.com
When first published in 1999, Your Drug May Be Your Problem was ahead of its time. The
only book to provide an uncensored description of the dangers involved in taking every kind …

Five year outcomes of tapering antipsychotic drug doses in a community mental health center

S Steingard - Community Mental Health Journal, 2018 - Springer
There is evidence that many individuals are on higher doses of antipsychotic drug than is
required for optimal functioning yet there are limited guidelines on how to reduce them. This …