[HTML][HTML] Predicting COVID-19—comorbidity pathway crosstalk-based targets and drugs: towards personalized COVID-19 management
It is well established that pre-existing comorbid conditions such as hypertension, diabetes,
obesity, cardiovascular diseases (CVDs), chronic kidney diseases (CKDs), cancers, and …
obesity, cardiovascular diseases (CVDs), chronic kidney diseases (CKDs), cancers, and …
Identifying molecular insight of synergistic complexities for SARS-CoV-2 infection with pre-existing type 2 diabetes
The ongoing COVID-19 outbreak, caused by SARS-CoV-2, has posed a massive threat to
global public health, especially to people with underlying health conditions. Type 2 diabetes …
global public health, especially to people with underlying health conditions. Type 2 diabetes …
Identification of Comorbidities, Genomic Associations, and Molecular Mechanisms for COVID‐19 Using Bioinformatics Approaches
Several studies have been done to identify comorbidities of COVID‐19. In this work, we
developed an analytical bioinformatics framework to reveal COVID‐19 comorbidities, their …
developed an analytical bioinformatics framework to reveal COVID‐19 comorbidities, their …
[HTML][HTML] Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug …
The pandemic threat of COVID-19 has severely destroyed human life as well as the
economy around the world. Although, the vaccination has reduced the outspread, but …
economy around the world. Although, the vaccination has reduced the outspread, but …
COVID-19: A drug repurposing and biomarker identification by using comprehensive gene-disease associations through protein-protein interaction network analysis
S Kumar - 2020 - preprints.org
Abstract COVID-19 (2019-nCoV) is a pandemic disease with an estimated mortality rate of
3.4%(estimated by the WHO as of March 3, 2020). Until now there is no antiviral drug and …
3.4%(estimated by the WHO as of March 3, 2020). Until now there is no antiviral drug and …
Multiomics integration-based molecular characterizations of COVID-19
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), rapidly became a global health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), rapidly became a global health …
[HTML][HTML] A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …
[HTML][HTML] Investigation of COVID-19 comorbidities reveals genes and pathways coincident with the SARS-CoV-2 viral disease
ME Dolan, DP Hill, G Mukherjee, MS McAndrews… - Scientific reports, 2020 - nature.com
The emergence of the SARS-CoV-2 virus and subsequent COVID-19 pandemic initiated
intense research into the mechanisms of action for this virus. It was quickly noted that COVID …
intense research into the mechanisms of action for this virus. It was quickly noted that COVID …
Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions
Despite the association of prevalent health conditions with coronavirus disease 2019
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …
[HTML][HTML] Multi-omic analysis reveals enriched pathways associated with COVID-19 and COVID-19 severity
COVID-19 is a disease characterized by its seemingly unpredictable clinical outcomes. In
order to better understand the molecular signature of the disease, a recent multi-omics study …
order to better understand the molecular signature of the disease, a recent multi-omics study …