The ability to anticipate and flexibly plan for the future is critical for achieving goal-directed
outcomes. Extant data suggest that neural and cognitive stress mechanisms may disrupt …

Mental representation of the future is a fundamental component of goal-directed behavior.
Computational and animal models highlight prospective spatial coding in the hippocampus …

Stress and stress hormones are known to influence the function of the hippocampus, a brain
structure critical for cognitive-map-based, allocentric spatial navigation. The caudate …

Planning spatial paths through our environment is an important part of everyday life and is
supported by a neural system including the hippocampus and prefrontal cortex. Here we …

Goal-directed behavior requires the representation of a task-set that defines the task-
relevance of stimuli and guides stimulus-action mappings. Past experience provides one …

Learning the location of relevant places in the environment is crucial for survival. Such
capacity is supported by a distributed network comprising the prefrontal cortex and …

INTRODUCTION Everyday life often requires arbitrating between pursuing an ongoing
action plan by possibly adjusting it versus exploring new action plans instead. Resolving this …

As we navigate the world, we use learned representations of relational structures to explore
and to reach goals. Studies of how relational knowledge enables inference and planning …

To guide spatial behavior, the brain must retrieve memories that are appropriately
associated with different navigational contexts. Contextual memory might be mediated by …

The ability to make adaptive decisions during goal-directed navigation is a fundamental and
highly evolved behavior that requires continual coordination of perceptions, learning and …